dc.contributor | Vall d'Hebron Barcelona Hospital Campus |
dc.contributor.author | Nunnally, Mark E. |
dc.contributor.author | Ferrer Roca, Ricard |
dc.contributor.author | Martin, Greg S. |
dc.contributor.author | Martin‑Loeches, Ignacio |
dc.contributor.author | Machado, Flavia R. |
dc.contributor.author | De Backer, Daniel |
dc.date.accessioned | 2022-02-25T12:33:24Z |
dc.date.available | 2022-02-25T12:33:24Z |
dc.date.issued | 2021-07-02 |
dc.identifier.citation | Nunnally ME, Ferrer R, Martin GS, Martin-Loeches I, Machado FR, De Backer D, et al. The Surviving Sepsis Campaign: research priorities for the administration, epidemiology, scoring and identification of sepsis. Intensive Care Med Exp. 2021 Jul 2;9:34. |
dc.identifier.issn | 2197-425X |
dc.identifier.uri | https://hdl.handle.net/11351/7082 |
dc.description | Epidemiology; Organ dysfunction; Sepsis |
dc.description.abstract | Objective
To identify priorities for administrative, epidemiologic and diagnostic research in sepsis.
Design
As a follow-up to a previous consensus statement about sepsis research, members of the Surviving Sepsis Campaign Research Committee, representing the European Society of Intensive Care Medicine and the Society of Critical Care Medicine addressed six questions regarding care delivery, epidemiology, organ dysfunction, screening, identification of septic shock, and information that can predict outcomes in sepsis.
Methods
Six questions from the Scoring/Identification and Administration sections of the original Research Priorities publication were explored in greater detail to better examine the knowledge gaps and rationales for questions that were previously identified through a consensus process.
Results
The document provides a framework for priorities in research to address the following questions: (1) What is the optimal model of delivering sepsis care?; (2) What is the epidemiology of sepsis susceptibility and response to treatment?; (3) What information identifies organ dysfunction?; (4) How can we screen for sepsis in various settings?; (5) How do we identify septic shock?; and (6) What in-hospital clinical information is associated with important outcomes in patients with sepsis?
Conclusions
There is substantial knowledge of sepsis epidemiology and ways to identify and treat sepsis patients, but many gaps remain. Areas of uncertainty identified in this manuscript can help prioritize initiatives to improve an understanding of individual patient and demographic heterogeneity with sepsis and septic shock, biomarkers and accurate patient identification, organ dysfunction, and ways to improve sepsis care. |
dc.language.iso | eng |
dc.publisher | Springer |
dc.relation.ispartofseries | Intensive Care Medicine Experimental;9 |
dc.rights | Attribution 4.0 International |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ |
dc.source | Scientia |
dc.subject | Xoc sèptic - Diagnòstic |
dc.subject | Medicina - Investigació |
dc.subject | Xoc sèptic - Prevenció |
dc.subject.mesh | Shock, Septic |
dc.subject.mesh | /diagnosis |
dc.subject.mesh | Research Design |
dc.title | The Surviving Sepsis Campaign: research priorities for the administration, epidemiology, scoring and identification of sepsis |
dc.type | info:eu-repo/semantics/article |
dc.identifier.doi | 10.1186/s40635-021-00400-z |
dc.subject.decs | choque séptico |
dc.subject.decs | /diagnóstico |
dc.subject.decs | diseño de la investigación |
dc.relation.publishversion | https://doi.org/10.1186/s40635-021-00400-z |
dc.type.version | info:eu-repo/semantics/publishedVersion |
dc.audience | Professionals |
dc.contributor.organismes | Institut Català de la Salut |
dc.contributor.authoraffiliation | [Nunnally ME] New York University School of Medicine, New York, NY, USA. [Ferrer R] Servei de Cures Intensives, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca en Xoc, Disfunció Orgànica i Reanimació, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Martin GS] Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Grady Memorial Hospital and Emory Critical Care Center, Emory University, Atlanta, GA, USA. [Martin-Loeches I] Multidisciplinary Intensive Care Research Organization (MICRO), Department of Intensive Care Medicine, St. James’s University Hospital, Trinity Centre for Health Sciences, Dublin, Ireland. Hospital Clinic, IDIBAPS, Universidad de Barcelona, CIBERes, Barcelona, Spain. [Machado FR] Universidade Federal de São Paulo, Sao Paulo, Brazil. [De Backer D] Chirec Hospitals, Université Libre de Bruxelles, Brussels, Belgium |
dc.identifier.pmid | 34212256 |
dc.identifier.wos | 000668892900001 |
dc.rights.accessrights | info:eu-repo/semantics/openAccess |