dc.contributor | Vall d'Hebron Barcelona Hospital Campus |
dc.contributor.author | Pascal, Mariona |
dc.contributor.author | Moreno, Carmen |
dc.contributor.author | Dávila, Ignacio |
dc.contributor.author | Tabar, Ana I. |
dc.contributor.author | Bartra, Joan |
dc.contributor.author | Labrador Horrillo, Moisés |
dc.contributor.author | Luengo Sanchez, Olga |
dc.date.accessioned | 2022-03-31T10:32:09Z |
dc.date.available | 2022-03-31T10:32:09Z |
dc.date.issued | 2021-08 |
dc.identifier.citation | Pascal M, Moreno C, Dávila I, Tabar AI, Bartra J, Labrador M, et al. Integration of in vitro allergy test results and ratio analysis for the diagnosis and treatment of allergic patients (INTEGRA). Clin Transl Allergy. 2021 Aug;11(7):e12052. |
dc.identifier.issn | 2045-7022 |
dc.identifier.uri | https://hdl.handle.net/11351/7287 |
dc.description | Allergy; Molecular diagnosis; Recommendations |
dc.description.abstract | The introduction of molecular diagnosis into routine clinical practice has substantially improved the diagnosis and management of allergic patients by allowing clinicians to precisely identify the allergenic molecule responsible for immunoglobulin E (IgE)-mediated allergies. However, it can be challenging to accurately interpret the results of molecular assays, partly due to the limited evidence base. In this context, a panel of experts with extensive experience in interpreting in vitro measures of total and serum specific IgE reviewed the available scientific evidence. After this review, the panel selected a series of representative case studies to demonstrate how determination of specific and total IgE values and the relationship between them (ratio analysis) can add value to the diagnostic process by more precisely defining the patient’s sensitization profile. Finally, the experts developed a series of recommendations on the clinical application of ratio analysis to optimize and complement the classical approach to allergy diagnosis. |
dc.language.iso | eng |
dc.publisher | Wiley |
dc.relation.ispartofseries | Clinical and Translational Allergy;11(7) |
dc.rights | Attribution 4.0 International |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ |
dc.source | Scientia |
dc.subject | Al·lèrgia - Diagnòstic |
dc.subject | Diagnòstic molecular |
dc.subject | Al·lèrgia - Tractament |
dc.subject.mesh | Hypersensitivity |
dc.subject.mesh | /diagnosis |
dc.subject.mesh | Molecular Diagnostic Techniques |
dc.title | Integration of in vitro allergy test results and ratio analysis for the diagnosis and treatment of allergic patients (INTEGRA) |
dc.type | info:eu-repo/semantics/article |
dc.identifier.doi | 10.1002/clt2.12052 |
dc.subject.decs | hipersensibilidad |
dc.subject.decs | /diagnóstico |
dc.subject.decs | técnicas de diagnóstico molecular |
dc.relation.publishversion | https://doi.org/10.1002/clt2.12052 |
dc.type.version | info:eu-repo/semantics/publishedVersion |
dc.audience | Professionals |
dc.contributor.organismes | Institut Català de la Salut |
dc.contributor.authoraffiliation | [Pascal M] Immunology Department, Centre de Diagnòstic Biomèdic, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain. ARADyAL Network, Health Institute Carlos III, Madrid, Spain. [Moreno C] ARADyAL Network, Health Institute Carlos III, Madrid, Spain. Allergy Service, Hospital Universitario Reina Sofía, Maimonides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain. [Dávila I] ARADyAL Network, Health Institute Carlos III, Madrid, Spain. Allergy Service, Department of Biomedical and Diagnostic Sciences and Institute for Biomedical Research of Salamanca (IBSAL), University Hospital of Salamanca, Salamanca, Spain. [Tabar AI] ARADyAL Network, Health Institute Carlos III, Madrid, Spain. Allergy Service, Hospital Complex of Navarra, Pamplona, Spain. Navarra Institute for Health Research (IdiSNA), Cooperative Health Research Thematic Networks (RETICs) for Asthma, Madrid, Spain. [Bartra J] ARADyAL Network, Health Institute Carlos III, Madrid, Spain. Allergy Section, Pneumology Department, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain. [Labrador M, Luengo O] ARADyAL Network, Health Institute Carlos III, Madrid, Spain. Secció d’Al·lèrgia, Servei de Medicina Interna, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain |
dc.identifier.pmid | 34582103 |
dc.identifier.wos | 000700512700002 |
dc.rights.accessrights | info:eu-repo/semantics/openAccess |