dc.contributor | Vall d'Hebron Barcelona Hospital Campus |
dc.contributor.author | Ruiz Rodriguez, Juan Carlos |
dc.contributor.author | Plata Menchaca, Erika Paola |
dc.contributor.author | Chiscano Camon, Luis Silvestre |
dc.contributor.author | Ruiz Sanmartin, Adolfo |
dc.contributor.author | Pérez Carrasco, Marcos |
dc.contributor.author | Palmada Ibars, Clara |
dc.contributor.author | Hernández González, Manuel |
dc.contributor.author | Gonzalez Lopez, Juan Jose |
dc.contributor.author | Larrosa Escartin, María Nieves |
dc.contributor.author | Ferrer Roca, Ricard |
dc.contributor.author | Martínez Gallo, Mónica |
dc.date.accessioned | 2022-09-06T12:45:12Z |
dc.date.available | 2022-09-06T12:45:12Z |
dc.date.issued | 2022-01-09 |
dc.identifier.citation | Ruiz-Rodriguez JC, Plata-Menchaca EP, Chiscano-Camón L, Ruiz-Sanmartin A, Pérez-Carrasco M, Palmada C, et al. Precision medicine in sepsis and septic shock: From omics to clinical tools. World J Crit care Med. 2022 Jan 9;11(1):1-21. |
dc.identifier.issn | 2220-3141 |
dc.identifier.uri | https://hdl.handle.net/11351/8040 |
dc.description | Endotype; Organ dysfunction; Sepsis |
dc.description.abstract | Sepsis is a heterogeneous disease with variable clinical course and several clinical phenotypes. As it is associated with an increased risk of death, patients with this condition are candidates for receipt of a very well-structured and protocolized treatment. All patients should receive the fundamental pillars of sepsis management, which are infection control, initial resuscitation, and multiorgan support. However, specific subgroups of patients may benefit from a personalized approach with interventions targeted towards specific pathophysiological mechanisms. Herein, we will review the framework for identifying subpopulations of patients with sepsis, septic shock, and multiorgan dysfunction who may benefit from specific therapies. Some of these approaches are still in the early stages of research, while others are already in routine use in clinical practice, but together will help in the effective generation and safe implementation of precision medicine in sepsis. |
dc.language.iso | eng |
dc.publisher | Baishideng Publishing Group |
dc.relation.ispartofseries | World journal of critical care medicine;11(1) |
dc.rights | Attribution-NonCommercial 4.0 International |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ |
dc.source | Scientia |
dc.subject | Medicina personalitzada |
dc.subject | Xoc sèptic |
dc.subject | Septicèmia |
dc.subject.mesh | Precision Medicine |
dc.subject.mesh | Shock, Septic |
dc.subject.mesh | Sepsis |
dc.title | Precision medicine in sepsis and septic shock: From omics to clinical tools |
dc.type | info:eu-repo/semantics/article |
dc.identifier.doi | 10.5492/wjccm.v11.i1.1 |
dc.subject.decs | medicina de precisión |
dc.subject.decs | choque séptico |
dc.subject.decs | sepsis |
dc.relation.publishversion | http://dx.doi.org/10.5492/wjccm.v11.i1.1 |
dc.type.version | info:eu-repo/semantics/publishedVersion |
dc.audience | Professionals |
dc.contributor.organismes | Institut Català de la Salut |
dc.contributor.authoraffiliation | [Ruiz-Rodriguez JC] Unitat de Cures Intensives, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca en Xoc, Disfunció Orgànica i Reanimació, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Plata-Menchaca EP] Grup de Recerca en Xoc, Disfunció Orgànica i Reanimació, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Department of Intensive Care, Hospital Clínic de Barcelona, Barcelona 08036, Spain. [Chiscano-Camón L, Ruiz-Sanmartin A, Ferrer R] Unitat de Cures Intensives, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca en Xoc, Disfunció Orgànica i Reanimació, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Pérez-Carrasco M] Unitat de Cures Intensives, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca en Xoc, Disfunció Orgànica i Reanimació, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Palmada C] Unitat de Cures Intensives, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Martínez-Gallo M, Hernández-González M] Servei d’Immunologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca en Immunologia Diagnòstica, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Departament de Biologia Cel•lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Gonzalez-Lopez JJ, Larrosa N] Servei de Microbiologia Clínica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Microbiologia i Genètica, Universitat Autònoma de Barcelona, Bellaterra, Spain |
dc.identifier.pmid | 35433311 |
dc.rights.accessrights | info:eu-repo/semantics/openAccess |