dc.contributor | Vall d'Hebron Barcelona Hospital Campus |
dc.contributor.author | Zuckerman, Scott L. |
dc.contributor.author | Cerpa, Meghan |
dc.contributor.author | Lenke, Lawrence G. |
dc.contributor.author | Shaffrey, Christopher I. |
dc.contributor.author | Carreon, Leah Y. |
dc.contributor.author | Cheung, Kenneth M. C. |
dc.contributor.author | Pellisé Uriquiza, Ferran |
dc.date.accessioned | 2022-11-03T13:20:36Z |
dc.date.available | 2022-11-03T13:20:36Z |
dc.date.issued | 2022-10 |
dc.identifier.citation | Zuckerman SL, Cerpa M, Lenke LG, Shaffrey CI, Carreon LY, Cheung KMC, et al. Patient-Reported Outcomes After Complex Adult Spinal Deformity Surgery: 5-Year Results of the Scoli-Risk-1 Study. Glob Spine J. 2022 Oct;12(8):1736–44. |
dc.identifier.issn | 2192-5690 |
dc.identifier.uri | https://hdl.handle.net/11351/8387 |
dc.description | Adult spinal deformity; Patient reported outcomes; Spinal deformity surgery |
dc.description.abstract | Study Design:
Prospective cohort.
Objective:
To prospectively evaluate PROs up to 5-years after complex ASD surgery.
Methods:
The Scoli-RISK-1 study enrolled 272 ASD patients undergoing surgery from 15 centers. Inclusion criteria was Cobb angle of >80°, corrective osteotomy for congenital or revision deformity, and/or 3-column osteotomy. The following PROs were measured prospectively at intervals up to 5-years postoperative: ODI, SF36-PCS/MCS, SRS-22, NRS back/leg. Among patients with 5-year follow-up, comparisons were made from both baseline and 2-years postoperative to 5-years postoperative. PROs were analyzed using mixed models for repeated measures.
Results:
Seventy-seven patients (28.3%) had 5-year follow-up data. Comparing baseline to 5-year data among these 77 patients, significant improvement was seen in all PROs: ODI (45.2 vs. 29.3, P < 0.001), SF36-PCS (31.5 vs. 38.8, P < 0.001), SF36-MCS (44.9 vs. 49.1, P = 0.009), SRS-22-total (2.78 vs. 3.61, P < 0.001), NRS-back pain (5.70 vs. 2.95, P < 0.001) and NRS leg pain (3.64 vs. 2.62, P = 0.017). In the 2 to 5-year follow-up period, no significant changes were seen in any PROs. The percentage of patients achieving MCID from baseline to 5-years were: ODI (62.0%) and the SRS-22r domains of function (70.4%), pain (63.0%), mental health (37.5%), self-image (60.3%), and total (60.3%). Surprisingly, mean values (P > 0.05) and proportion achieving MCID did not differ significantly in patients with major surgery-related complications compared to those without.
Conclusions:
After complex ASD surgery, significant improvement in PROs were seen at 5-years postoperative in ODI, SF36-PCS/MCS, SRS-22r, and NRS-back/leg pain. No significant changes in PROs occurred during the 2 to 5-year postoperative period. Those with major surgery-related complications had similar PROs and proportion of patients achieving MCID as those without these complications. |
dc.language.iso | eng |
dc.publisher | SAGE Publications |
dc.relation.ispartofseries | Global Spine Journal;12(8) |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
dc.source | Scientia |
dc.subject | Columna vertebral - Malformacions - Cirurgia |
dc.subject | Cirurgia - Complicacions |
dc.subject | Pacients - Satisfacció |
dc.subject.mesh | Spinal Diseases |
dc.subject.mesh | /surgery |
dc.subject.mesh | Postoperative Complications |
dc.subject.mesh | Patient Reported Outcome Measures |
dc.title | Patient-Reported Outcomes After Complex Adult Spinal Deformity Surgery: 5-Year Results of the Scoli-Risk-1 Study |
dc.type | info:eu-repo/semantics/article |
dc.identifier.doi | 10.1177/2192568220988276 |
dc.subject.decs | enfermedades de la columna vertebral |
dc.subject.decs | /cirugía |
dc.subject.decs | complicaciones posoperatorias |
dc.subject.decs | medidas de resultados percibidos por los pacientes |
dc.relation.publishversion | https://doi.org/10.1177/2192568220988276 |
dc.type.version | info:eu-repo/semantics/publishedVersion |
dc.audience | Professionals |
dc.contributor.organismes | Institut Català de la Salut |
dc.contributor.authoraffiliation | [Zuckerman SL, Cerpa M, Lenke LG] Columbia University Medical Center, New York, NY, USA. [Shaffrey CI] Duke University Medical Center, Durham, NC, USA. [Carreon LY] Norton Leatherman Spine Center, Louisville, KY, USA. [Cheung KMC] Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong. [Pellisé F] Vall d’Hebron Hospital Universitari, Barcelona, Spain |
dc.identifier.pmid | 33557622 |
dc.identifier.wos | 000682187900001 |
dc.rights.accessrights | info:eu-repo/semantics/openAccess |