%PDF-1.4
%
1 0 obj
<<
/Metadata 2 0 R
/Outlines 3 0 R
/PageLabels 4 0 R
/Pages 5 0 R
/Type /Catalog
/Names 6 0 R
>>
endobj
7 0 obj
<<
/ModDate (D:20190415155103+05'30')
/Producer (Acrobat Distiller 10.0.0 \(Windows\))
/Creator (Arbortext Advanced Print Publisher 9.1.510/W Unicode)
/CreationDate (D:20190415155039+05'30')
>>
endobj
2 0 obj
<<
/Type /Metadata
/Subtype /XML
/Length 8 0 R
>>
stream
doi:10.1200/JCO.18.02031
Phase III Trial of PROSTVAC in Asymptomatic or Minimally Symptomatic Metastatic Castration-Resistant Prostate Cancer
10.1200/JCO.18.02031
http://dx.doi.org/10.1200/JCO.18.02031
2019-04-15
false
10.1200/JCO.18.02031
http://ascopubs.org/
http://ascopubs.org/
10.1200/JCO.18.02031
2019-04-15
false
http://ascopubs.org/
endstream
endobj
3 0 obj
<<
/Count 1
/First 9 0 R
/Last 9 0 R
>>
endobj
4 0 obj
<<
/Nums [0 10 0 R]
>>
endobj
5 0 obj
<<
/Count 12
/Type /Pages
/Kids [11 0 R 12 0 R]
>>
endobj
6 0 obj
<<
/Dests 13 0 R
>>
endobj
8 0 obj
1754
endobj
9 0 obj
<<
/First 14 0 R
/Dest
/Title
/Parent 3 0 R
/Last 15 0 R
/Count -6
>>
endobj
10 0 obj
<<
/S /D
>>
endobj
11 0 obj
<<
/Count 10
/Parent 5 0 R
/Type /Pages
/Kids [16 0 R 17 0 R 18 0 R 19 0 R 20 0 R 21 0 R 22 0 R 23 0 R 24 0 R 25 0 R]
>>
endobj
12 0 obj
<<
/Count 2
/Parent 5 0 R
/Type /Pages
/Kids [26 0 R 27 0 R]
>>
endobj
13 0 obj
<<
/Kids [28 0 R 29 0 R]
>>
endobj
14 0 obj
<<
/Parent 9 0 R
/Dest
/Next 30 0 R
/Title
>>
endobj
15 0 obj
<<
/Parent 9 0 R
/Dest
/Prev 31 0 R
/Title
>>
endobj
16 0 obj
<<
/CropBox [0 0 584.9569702148 782.9860229492]
/MediaBox [0 0 584.9569702148 782.9860229492]
/Annots [32 0 R 33 0 R 34 0 R 35 0 R 36 0 R 37 0 R 38 0 R 39 0 R 40 0 R 41 0 R
42 0 R 43 0 R]
/Rotate 0
/Resources 44 0 R
/Thumb 45 0 R
/Parent 11 0 R
/Contents [46 0 R 47 0 R 48 0 R 49 0 R 50 0 R 51 0 R 52 0 R 53 0 R]
/Type /Page
>>
endobj
17 0 obj
<<
/CropBox [0 0 584.9569702148 782.9860229492]
/MediaBox [0 0 584.9569702148 782.9860229492]
/Annots [54 0 R 55 0 R 56 0 R 57 0 R 58 0 R 59 0 R 60 0 R 61 0 R]
/Rotate 0
/Resources 62 0 R
/Thumb 63 0 R
/Parent 11 0 R
/Contents 64 0 R
/Type /Page
>>
endobj
18 0 obj
<<
/CropBox [0 0 584.9569702148 782.9860229492]
/MediaBox [0 0 584.9569702148 782.9860229492]
/Annots [65 0 R 66 0 R 67 0 R 68 0 R 69 0 R 70 0 R 71 0 R 72 0 R]
/Rotate 0
/Resources 73 0 R
/Thumb 74 0 R
/Parent 11 0 R
/Contents 75 0 R
/Type /Page
>>
endobj
19 0 obj
<<
/CropBox [0 0 584.9569702148 782.9860229492]
/MediaBox [0 0 584.9569702148 782.9860229492]
/Annots [76 0 R]
/Rotate 0
/Resources 77 0 R
/Thumb 78 0 R
/Parent 11 0 R
/Contents 79 0 R
/Type /Page
>>
endobj
20 0 obj
<<
/CropBox [0 0 584.9569702148 782.9860229492]
/MediaBox [0 0 584.9569702148 782.9860229492]
/Rotate 0
/Thumb 80 0 R
/Resources 81 0 R
/Parent 11 0 R
/Contents 82 0 R
/Type /Page
>>
endobj
21 0 obj
<<
/CropBox [0 0 584.9569702148 782.9860229492]
/MediaBox [0 0 584.9569702148 782.9860229492]
/Annots [83 0 R 84 0 R 85 0 R 86 0 R 87 0 R 88 0 R 89 0 R 90 0 R 91 0 R 92 0 R
93 0 R 94 0 R 95 0 R]
/Rotate 0
/Resources 96 0 R
/Thumb 97 0 R
/Parent 11 0 R
/Contents 98 0 R
/Type /Page
>>
endobj
22 0 obj
<<
/CropBox [0 0 584.9569702148 782.9860229492]
/MediaBox [0 0 584.9569702148 782.9860229492]
/Annots [99 0 R 100 0 R 101 0 R 102 0 R 103 0 R 104 0 R 105 0 R 106 0 R]
/Rotate 0
/Resources 107 0 R
/Thumb 108 0 R
/Parent 11 0 R
/Contents 109 0 R
/Type /Page
>>
endobj
23 0 obj
<<
/CropBox [0 0 584.9569702148 782.9860229492]
/MediaBox [0 0 584.9569702148 782.9860229492]
/Annots [110 0 R]
/Rotate 0
/Resources 111 0 R
/Thumb 112 0 R
/Parent 11 0 R
/Contents 113 0 R
/Type /Page
>>
endobj
24 0 obj
<<
/CropBox [0 0 584.9569702148 782.9860229492]
/MediaBox [0 0 584.9569702148 782.9860229492]
/Annots [114 0 R 115 0 R 116 0 R 117 0 R 118 0 R 119 0 R 120 0 R 121 0 R 122 0 R 123 0 R
124 0 R 125 0 R]
/Rotate 0
/Resources 126 0 R
/Thumb 127 0 R
/Parent 11 0 R
/Contents 128 0 R
/Type /Page
>>
endobj
25 0 obj
<<
/CropBox [0 0 584.9569702148 782.9860229492]
/MediaBox [0 0 584.9569702148 782.9860229492]
/Rotate 0
/Thumb 129 0 R
/Resources 130 0 R
/Parent 11 0 R
/Contents 131 0 R
/Type /Page
>>
endobj
26 0 obj
<<
/CropBox [0 0 584.9569702148 782.9860229492]
/MediaBox [0 0 584.9569702148 782.9860229492]
/Rotate 0
/Thumb 132 0 R
/Resources 133 0 R
/Parent 12 0 R
/Contents 134 0 R
/Type /Page
>>
endobj
27 0 obj
<<
/CropBox [0 0 584.9569702148 782.9860229492]
/MediaBox [0 0 584.9569702148 782.9860229492]
/Annots [135 0 R 136 0 R]
/Rotate 0
/Resources 137 0 R
/Thumb 138 0 R
/Parent 12 0 R
/Contents 139 0 R
/Type /Page
>>
endobj
28 0 obj
<<
/Limits [ ]
/Names [ 140 0 R 141 0 R 142 0 R 143 0 R 144 0 R
145 0 R 146 0 R 147 0 R 148 0 R 149 0 R
150 0 R 151 0 R 152 0 R 153 0 R 154 0 R
155 0 R 156 0 R 157 0 R 158 0 R 159 0 R
160 0 R 161 0 R 162 0 R 163 0 R 164 0 R
165 0 R 166 0 R 167 0 R 168 0 R 169 0 R
170 0 R 171 0 R 172 0 R 173 0 R 174 0 R
175 0 R 176 0 R 177 0 R 178 0 R 179 0 R
180 0 R 181 0 R 182 0 R 183 0 R 184 0 R
185 0 R 186 0 R 187 0 R 188 0 R 189 0 R
190 0 R 191 0 R 192 0 R 193 0 R 194 0 R
195 0 R 196 0 R 197 0 R 198 0 R 199 0 R
200 0 R 201 0 R 182 0 R 182 0 R]
>>
endobj
29 0 obj
<<
/Limits [ ]
/Names [ 182 0 R 183 0 R 183 0 R 183 0 R 183 0 R
183 0 R 202 0 R 181 0 R]
>>
endobj
30 0 obj
<<
/First 203 0 R
/Prev 14 0 R
/Dest
/Title
/Next 204 0 R
/Last 205 0 R
/Parent 9 0 R
/Count -4
>>
endobj
31 0 obj
<<
/Prev 206 0 R
/Dest
/Title
/Next 15 0 R
/Parent 9 0 R
>>
endobj
32 0 obj
<<
/Rect [211.4640045166 160.1009979248 214.9230041504 168.4349975586]
/Dest
/Subtype /Link
/Border [0 0 0]
/Type /Annot
>>
endobj
33 0 obj
<<
/Rect [216.6239929199 160.1009979248 220.0249938965 168.4349975586]
/Dest
/Subtype /Link
/Border [0 0 0]
/Type /Annot
>>
endobj
34 0 obj
<<
/Rect [265.2090148926 124.2710037231 268.6109924316 132.5480041504]
/Dest
/Subtype /Link
/Border [0 0 0]
/Type /Annot
>>
endobj
35 0 obj
<<
/Rect [270.6520080566 124.2710037231 274.0530090332 132.5480041504]
/Dest
/Subtype /Link
/Border [0 0 0]
/Type /Annot
>>
endobj
36 0 obj
<<
/Rect [248.9949951172 88.3840026855 252.6239929199 96.7180023193]
/Dest
/Subtype /Link
/Border [0 0 0]
/Type /Annot
>>
endobj
37 0 obj
<<
/Rect [254.8350067139 88.3840026855 258.4630126953 96.7180023193]
/Dest
/Subtype /Link
/Border [0 0 0]
/Type /Annot
>>
endobj
38 0 obj
<<
/Rect [167.3569946289 76.4219970703 173.5939941406 84.7559967041]
/Dest
/Subtype /Link
/Border [0 0 0]
/Type /Annot
>>
endobj
39 0 obj
<<
/Rect [318.1610107422 76.4219970703 324.4530029297 84.7559967041]
/Dest
/Subtype /Link
/Border [0 0 0]
/Type /Annot
>>
endobj
40 0 obj
<<
/Rect [527.3569946289 88.78099823 534.0469970703 97.1149978638]
/Dest
/Subtype /Link
/Border [0 0 0]
/Type /Annot
>>
endobj
41 0 obj
<<
/Rect [77.4420013428 268.1570129395 98.8720016479 275.6409912109]
/Subtype /Link
/A 207 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
42 0 obj
<<
/Rect [49.7200012207 248.2019958496 104.3720016479 255.6849975586]
/Subtype /Link
/A 208 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
43 0 obj
<<
/Rect [36.9640007019 238.2799987793 99.15599823 245.7070007324]
/Subtype /Link
/A 209 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
44 0 obj
<<
/ProcSet [/PDF /Text]
/ExtGState 210 0 R
/Font 211 0 R
/Properties 212 0 R
/ColorSpace 213 0 R
>>
endobj
45 0 obj
<<
/Height 97
/BitsPerComponent 8
/Length 214 0 R
/ColorSpace [/Indexed /DeviceRGB 255 215 0 R]
/Width 73
/Filter [/ASCII85Decode /FlateDecode]
>>
stream
8;Z\799OrN%!?'F]ogj8_I]q)9?`D[:JR>D9Rre/!MQ>S2:YRblcVr:J;@QXMa0A&
=j7<(*9?a6(NPGG\CIsBPc3cB'Kq_mdDM2eCE&$$-(Qbb&bfPFV@doUI:CB)I5Z#u
h">4]!,&^n+8A@+Qa/!L\YL]]nW`%dYW2ooBRQYc4V+@$(M;tV8pFp:>TJ7M!RR_N
@#*C>:t\&.Fr?Wp`Jt^ao_Qjr\d/D)Y,*_h-pWU5"
XWuX/kT;VWb->W%qc6cK>9Kl"OFabI<,YsHF`_O*";pO-H+0;a2C<1@/.prn;3L28
J=;pmVNpLn`&*_$:H%SDC+@0AULQg%E;%lCn_"*HFH[P.5er=t[p#L456u\UkAEGFW,JBMk.U,EPTkYbp`p`[0e*cb4;,"RWtKU[Q9M'3fEKDU#4Pi66>;cKcW6G3-5eGR
0O/A4NoTnej+uo:05<1B)3>k#re/lm:FZ084iVb4gj]]\m]??r!6V5H0E~>
endstream
endobj
46 0 obj
<<
/Filter /FlateDecode
/Length 216 0 R
>>
stream
HWMs6WHX0ALOĭkiCFf,%PJ3[|Ȓk:-,>}^?E7n7;vv5b2:;|o#ɖlW2-3)wߎlͷk| ös̽Jv}c |$BZ8敁8iYnd
dd bQkјbδ#Y6SM|i>c9tx̯hFA iex.B3vDbPpmC,Ctq-qlrMٖe4sc|Nr5RLR _IlrFڕ OSd}y}gO٠qa
?9^6}QσVM,\;pIne(e,@t6ُчo.oOƪVW1wU^,nmN]"JAA:B,c)GT=CuhXk]yj/b\W7Ng^Lʲ̼ޯ5 #ȹt=4\UWrݬV ,UӃ9UkG<*!`Lo7;4hc>3c$ay|V$hhl햂H[ڤ^_ӄg8M@ lqQ SpC¨ХTd
Q}Pb+HFViW λoOSjBAt>JyRPQPu3%Q`տj1j]~ ˣ&XE]fJg.#1O#1֢ k*yxp=J}UDT,r>6n@32J^S]n/m&ap_8U$ZSxiphpa/SQ5PL}0/1APW!{?T~@>SG82z2}7nn>v}a4DK
i d.-/TժY&@3C@a@i49KF4ݞeiV8?"ŀ%;S!pW}ei&4?ixn) .rKĎr-ATm8FWݨKLF"b#hQchz:UG@mj|_MiJ|&o|N8v.<' E]T"U^@jh~T&C? M-.x^}mQ1oynAoel$>w~}^j.4A)O 9Uu
endstream
endobj
47 0 obj
<<
/Filter /FlateDecode
/Length 217 0 R
>>
stream
HWr6ntX0^|`<]xb'u؞XqIIh$RCRʨnH[rv0@ :d<$&H_LskE2JeΓ,U;ONa7 ̻UK_,֯8ۢZ|;x.ݗߧnESTs9J2A˰Tsc}x.jָ=ܲzֻEb;HιB=CDT$8]5[AVUW'+6Db]"c9A<{-Gr4DfjEQ$A1R%U+l-./OX횢TZnR0RJf ?H$Ryw_Eq&EKD%x~p
>IR*hAXFƕ]oNh))(uAǗu3$9~VutMٓnzUWxMsVpyXm"68ZePNdJO#Rm#dxn.mإͪ(ݗyPp
h% :,(IZêa]vA
EUv92HwME6K)B:2vٞRK`j>p;r
mC T;v~hXDubt>'y|hQ? X"OyqswZڐɈ:Ioq$QfzE.]mU_Wz:!z.u8d9$hyL",l9"(M6+VQV. o}&ljvAhJ![oWZ (͋PQ{tÛ=U`U7UQeS H{yQ
y@^d2ɔh"~cBʌ'#B)FQ>}O(Q`Ado45~]4{:C+$Yh$Ӧ)H1C^!ގ
Ҟt{χ#ЉdD'HTTdƢjzVE={e+ӓƨx[CU&zAۀ(]ਡE8
Ĥop}fKr!2*nEςflԵ2*Uu)ͲM6:+n=tmF+µOdny<0Jg/!B#o>~B-5%B·OD/-1@8ӂ#jCWOR? d]Rb;)sѮqX[fhg*t;އ.-3{u-{!j]*'%@B
4}{ߥqyEM?8}&y,eK!>z&~]ٸehVa4=8@~'IoQu
}/Y\2c䎴*wŶNXӡG:Txd";!}a4IQe618^]%(8GR4!0NLΰ<}
endstream
endobj
48 0 obj
<<
/Filter /FlateDecode
/Length 218 0 R
>>
stream
HWrF}WEU3}N*$rV\!,$$}R2RrU[~L_N^Y\~S*lz{o^ʤS_?ϗV22q6jѵԥUΗnҫ]KySwhW?&T:U]Y,m,X҆%~-H\a7 svݶHҨwblͥ?#LLV
Q׳p.j\ݷlۦR\#DGSGxpb