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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorFernández Fuertes, Luis Fernando
dc.contributor.authorGonzález-López, Tomás José
dc.contributor.authorGuinea de Castro, José María
dc.contributor.authorJarque, Isidro
dc.contributor.authorValcarcel Ferreiras, David
dc.contributor.authorMingot-Castellano, M.E.
dc.contributor.authorÁlvarez Román, María Teresa
dc.date.accessioned2020-07-29T07:32:11Z
dc.date.available2020-07-29T07:32:11Z
dc.date.issued2019-08-22
dc.identifier.citationMingot-Castellano ME, Román MT, Fernández Fuertes LF, González-López T, Guinea de Castro JM, Jarque I, et al. Management of adult patients with primary immune thrombocytopenia (ITP) in clinical practice: a consensus approach of the Spanish ITP expert group. Adv Hematol. 2019;2019:4621416.
dc.identifier.issn1687-9104
dc.identifier.urihttp://hdl.handle.net/11351/5117
dc.descriptionDelphi method; Primary immune thrombocytopenia; Clinical guideline
dc.description.abstractBackground and Objective. Diagnosis and management of primary immune thrombocytopenia (ITP) have changed dramatically in the last decade. Te aim of the study was to obtain information about the opinion of the Spanish ITP Group (GEPTI) members regarding the best clinical practices for diagnosis and management of adult patients with ITP. Materials and Methods. A tworound Delphi method was carried out by sending to 129 experts a 90-item questionnaire developed by 11 specialists, with a 4-point Likert scale (“never,” “sometimes,” “frequently,” and “always”) for the assessment of responses. Results. Forty out of the 129 experts participated in the survey (participation rate 30.2%) and 39 completed the questionnaire (response rate 97.5%). Salient consensus points included the following: the need to indicate workup studies from a sustained platelet count < 100 x 109 /L in the absence of a clear etiology; bone marrow aspiration in elderly patients with suspected ITP; beginning treatment in asymptomatic patients with a platelet count < 20 x 109 /L; not exceeding 6-7 weeks of corticosteroid therapy; switching from corticosteroids to one thrombopoietin receptor agonist (TRA); switching to other TRA or other options as combinations of them with immunosuppressive drugs in case of failure; how to reduce tapering TRA; treating patients with symptomatic persistent ITP and platelet count > 20 x 109 /L; and considering mucosal or severe bleeding as a basic criterion for hospital admission. Conclusions. Te present consensus document provides a reference framework for the management of patients with ITP in clinical practice.
dc.language.isoeng
dc.publisherHindawi
dc.relation.ispartofseriesAdvances in Hematology;2019
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectEquips d'especialistes
dc.subjectTrombocitopènia
dc.subjectProtocols clínics
dc.subject.meshDelphi Technique
dc.subject.meshThrombocytopenia
dc.subject.meshClinical Protocols
dc.titleManagement of adult patients with primary immune thrombocytopenia (ITP) in clinical practice: a consensus approach of the Spanish ITP expert group
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1155/2019/4621416
dc.subject.decstécnica Delfos
dc.subject.decstrombocitopenia
dc.subject.decsprotocolos clínicos
dc.relation.publishversionhttps://www.hindawi.com/journals/ah/2019/4621416/
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.authoraffiliation[Mingot-Castellano ME] Service of Hematology, Hospital Virgen del Rocio, Sevilla, Spain. [Álvarez Román MT] Service of Hematology, Hospital Universitario La Paz, Madrid, Spain. [Fernández Fuertes LF] Service of Hematology, Complejo Hospitalario Universitario Insular Materno-Infantil, Las Palmas de Gran Canaria, Spain. [González-López TJ] Service of Hematology, Hospital Universitario de Burgos, Burgos, Spain. [Guinea de Castro JM] Service of Hematology and Hemotherapy, Universitario de Araba, Vitoria-Gasteiz, Álava, Spain. [Jarque I] Service of Hematology and Hemotherapy, Hospital Universitario y Politécnico La Fe, Valencia, Spain. [Valcárcel Ferreiras D] Unitat de Trasplantament de cèl•lules mare hematopoètiques, Vall d'Hebron Hospital Universitari, Barcelona, Spain
dc.identifier.pmid31534457
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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