Show simple item record

 
dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorJiménez de Ory, Santiago
dc.contributor.authorRamos, José Tomas
dc.contributor.authorFortuny, Clàudia
dc.contributor.authorGonzález-Tomé, María Isabel
dc.contributor.authorMellado, Maria José
dc.contributor.authorMoreno, David
dc.contributor.authorFrick, Marie Antoinette
dc.date.accessioned2020-09-01T10:57:17Z
dc.date.available2020-09-01T10:57:17Z
dc.date.issued2019-10-24
dc.identifier.citationJiménez de Ory S, Ramos JT, Fortuny C, González-Tomé MI, Mellado MJ, Moreno D, et al. Sociodemographic changes and trends in the rates of new perinatal HIV diagnoses and transmission in Spain from 1997 to 2015. PLoS One. 2019 Oct 24;14(10):e0223536.
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/11351/5196
dc.descriptionRetrospective study; Spanish Paediatric HIV Network; Rates of perinatal HIV
dc.description.abstractBackground: There are not enough nationwide studies on perinatal HIV transmission in connection with a combination of antiretroviral treatments in Spain. Our objectives were to study sociodemographic changes and trends in the rates of HIV diagnoses and perinatal transmission in Spain from 1997 to 2015. Methods: A retrospective study using data from Spanish Paediatric HIV Network (CoRISpe) and Spanish Minimum Basic Data Set (MDBS) was performed. HIV- diagnosed children between 1997 and 2015 were selected. Sociodemographic, clinical and immunovirological data of HIV-infected children and their mothers were studied in four calendar periods (P1: 1997-2000; P2: 2001-2005; P3: 2006-2010; P4: 2011-2015). Rates of perinatal HIV diagnoses and transmission from 1997 to 2015 were calculated. Results: A total of 532 HIV-infected children were included in this study. Of these children, 406 were Spanish (76.3%) and 126 immigrants (23.7%). A decrease in the number of HIV diagnoses, 203 (38.2%) children in the first (P1), 149 (28%) in the second (P2), 130 (24.4%) in the third (P3) and 50 (9.4%) in the fourth (P4) calendar periods was studied. The same decrease in the Spanish HIV-infected children (P1, 174 (46.6%), P2, 115 (30.8%), P3, 65 (17.4%) and P4, 19 (5.1%)) was monitored. However, an increase in the number of HIV diagnoses by sexual contact (P1: 0%; P2: 1.3%; P3: 4.6%; P4: 16%) was observed. The rates of new perinatal HIV diagnoses and perinatal transmission in Spanish children decreased from 0.167 to 0.005 per 100,000 inhabitants and 11.4% to 0.4% between 1997 and 2015, respectively. Conclusions: A decline of perinatal HIV diagnoses and transmission was observed. However, an increase of teen-agers HIV diagnoses with sexual infection was studied. Public awareness campaigns directed to teen-agers are advisable to prevent HIV infection by sexual contact.
dc.language.isoeng
dc.publisherPublic Library of Science
dc.relation.ispartofseriesPLoS One;14(10)
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectInfeccions per VIH
dc.subjectEstudi de casos - Espanya
dc.subject.meshHIV Infections
dc.subject.meshRetrospective Studies
dc.subject.meshSpain
dc.titleSociodemographic changes and trends in the rates of new perinatal HIV diagnoses and transmission in Spain from 1997 to 2015
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1371/journal.pone.0223536
dc.subject.decsinfecciones por VIH
dc.subject.decsestudios retrospectivos
dc.subject.decsEspaña
dc.relation.publishversionhttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223536
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.authoraffiliation[Jiménez de Ory S] Hospital General Universitario Gregorio Marañón, Madrid, Spain. Instituto de Investigación Sanitaria Gregorio Marañón (IisGM), Madrid, Spain. CoRISpe, Madrid, Spain. [Ramos JT] Servicio de Pediatría, Hospital Clínico San Carlos, Madrid, Spain. Universidad Complutense de Madrid, Madrid, Spain. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain. [Fortuny C] Unidad de Enfermedades Infecciosas, Servicio de Pediatría, Hospital Sant Joan de Déu, Esplugues del Llobregat, Spain. Universitat de Barcelona, Barcelona, Spain. [González-Tomé MI] Servicio de Infecciosas Pediátricas, Hospital Universitario Doce de Octubre, Madrid, Spain. Instituto de Investigación Hospital 12 de Octubre, Madrid, Spain. Universidad Complutense de Madrid, Madrid, Spain. [Mellado MJ] Pediatrics, Immunodeficiencies and Infectious Diseases Unit, Hospital Universitario La Paz, Madrid, Spain. Translational Research Network in Pediatric Infectious Diseases (RITIP), Madrid, Spain. [Moreno D] Department of Pediatrics, Regional Maternal-Child University Hospital, Malaga, Spain. IBIMA Multidisciplinary Group for Pediatric Research, Malaga, Spain, Malaga University, Malaga, Spain. [Frick MA] Unitat de Medicina tropical i Salut internacional, Vall d'Hebron Hospital Universitari, Barcelona, Spain. Servei de Pediatria, Vall d'Hebron Hospital Universitari, Barcelona, Spain. PROSICS Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain
dc.identifier.pmid31647824
dc.identifier.wos000532631800023
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/6PN/RD12%2F0017%2F0035
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/6PN/RD12%2F0017%2F0037
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/PE2013-2016/RD16%2F0025%2F0019
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/PE2013-2016/PI13%2F00422
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/PE2013-2016/PI16%2F01863
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


Files in this item

Thumbnail
Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record