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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorFrank, Derk
dc.contributor.authorKennon, Simon
dc.contributor.authorBonaros, Nikolaos
dc.contributor.authorStastny, Lukas
dc.contributor.authorRomano, Mauro
dc.contributor.authorLefèvre, Thierry
dc.contributor.authorGarcía Blanco, Bruno
dc.date.accessioned2021-05-14T12:17:33Z
dc.date.available2021-05-14T12:17:33Z
dc.date.issued2021-02
dc.identifier.citationFrank D, Kennon S, Bonaros N, Stastny L, Romano M, Lefèvre T, et al. Aortic valve replacement: validation of the Toronto Aortic Stenosis Quality of Life Questionnaire. ESC Hear Fail. 2021 Feb;8(1):270-279.
dc.identifier.issn2055-5822
dc.identifier.urihttp://hdl.handle.net/11351/5950
dc.descriptionAortic valve replacement; Quality of life; Questionnaire
dc.description.abstractAims There is no quality of life tool specifically developed for patients with severe aortic stenosis (AS) to assess how this chronic condition and its treatment affect patients. The Toronto Aortic Stenosis Quality of Life Questionnaire (TASQ) has been developed to overcome this gap. The results of the validation of the TASQ in patients undergoing treatment for severe AS are presented. Methods and results Prospective study at 10 centres in Europe and Canada, which enrolled 274 patients with severe symptomatic AS undergoing surgical or transcatheter aortic valve replacement. Mean TASQ score at baseline was 71.2 points and increased to 88.9 three months after aortic valve implantation (P < 0.001). Increases were seen for the emotional impact (32.0 to 39.0; P < 0.001), physical limitations (14.8 to 22.0; P < 0.001), and physical symptoms (8.5 vs. 11.0; P < 0.001) domains. Internal consistency was good/excellent for overall TASQ score (α = 0.891) and for the physical limitation, emotional impact, and social limitation domains (α = 0.815–0.950). Test–retest reliability was excellent or strong for the overall TASQ (intraclass correlation coefficient of 0.883) and for the physical symptoms, physical limitation, emotional impact, and social limitation domains (intraclass correlation coefficient of 0.791–0.895). Responsiveness was medium overall (Cohen's d = 0.637) and medium/large for physical symptoms, emotional impact, and physical limitations (0.661–0.812). Sensitivity to change was significant for physical symptoms, physical limitations (both P < 0.001), emotional impact (P = 0.003), and social limitations (P = 0.038). Conclusions The TASQ is a new, brief, self‐administered, and clinically relevant health‐specific tool to measure changes in quality of life in patients with AS undergoing an intervention.
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofseriesESC Heart Failure;8(1)
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceScientia
dc.subjectVàlvula aòrtica - Estenosi
dc.subjectPròtesis valvulars cardíaques
dc.subjectPacients - Satisfacció
dc.subject.meshAortic Valve Stenosis
dc.subject.meshTranscatheter Aortic Valve Replacement
dc.subject.meshQuality of Life
dc.titleAortic valve replacement: validation of the Toronto Aortic Stenosis Quality of Life Questionnaire
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1002/ehf2.12961
dc.subject.decsestenosis de la válvula aórtica
dc.subject.decssustitución valvular aórtica con catéter
dc.subject.decscalidad de vida
dc.relation.publishversionhttps://doi.org/10.1002/ehf2.12961
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Frank D] Department of Internal Medicine III (Cardiology, Angiology and Critical Care), UKSH University Clinical Center Schleswig‐Holstein, and DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Arnold‐Heller Strasse 3, Kiel, 24105, Germany. [Kennon S] Department of Cardiology, Barts Heart Centre, St. Bartholomew’s Hospital, London, UK. [Bonaros N, Stastny L] Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria. [Romano M, Lefèvre T] Department of Thoracic and Cardiovascular Surgery, Department of Interventional Cardiology, Hôpital Privé Jacques Cartier, Massy, France. [Garcia Del Blanco B] Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. CIBER CV, Barcelona, Spain
dc.identifier.pmid33207035
dc.identifier.wos000590122800001
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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