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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorOceja, Esther
dc.contributor.authorRodríguez, Paula
dc.contributor.authorJurado Luque, Mª Jose
dc.contributor.authorAlonso, Maria Luz
dc.contributor.authordel Río, Genoveva
dc.contributor.authorVillar, María Ángeles
dc.date.accessioned2021-07-13T11:58:23Z
dc.date.available2021-07-13T11:58:23Z
dc.date.issued2021-01-19
dc.identifier.citationOceja E, Rodríguez P, Jurado M, Luz Alonso M, Del Río G, Villar M, et al. Validity and Cost-Effectiveness of Pediatric Home Respiratory Polygraphy for the Diagnosis of Obstructive Sleep Apnea in Children: Rationale, Study Design, and Methodology. Methods Protoc. 2021 Jan 19;4(1):9.
dc.identifier.issn2409-9279
dc.identifier.urihttp://hdl.handle.net/11351/6154
dc.descriptionCost-effectiveness analysis; Obstructive sleep apnea (OSA); Respiratory polygraphy
dc.description.abstractObstructive sleep apnea (OSA) in children is a prevalent, albeit largely undiagnosed disease associated with a large spectrum of morbidities. Overnight in-lab polysomnography remains the gold standard diagnostic approach, but is time-consuming, inconvenient, and expensive, and not readily available in many places. Simplified Home Respiratory Polygraphy (HRP) approaches have been proposed to reduce costs and facilitate the diagnostic process. However, evidence supporting the validity of HRP is still scarce, hampering its implementation in routine clinical use. The objectives were: Primary; to establish the diagnostic and therapeutic decision validity of a simplified HRP approach compared to PSG among children at risk of OSA. Secondary: (a) Analyze the cost-effectiveness of the HRP versus in-lab PSG in evaluation and treatment of pediatric OSA; (b) Evaluate the impact of therapeutic interventions based on HRP versus PSG findings six months after treatment using sleep and health parameters and quality of life instruments; (c) Discovery and validity of the urine biomarkers to establish the diagnosis of OSA and changes after treatment.
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofseriesMethods and Protocols;4(1)
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectSíndromes d'apnea del son - Diagnòstic
dc.subjectCost-eficàcia
dc.subject.meshCost-Benefit Analysis
dc.subject.meshPolysomnography
dc.subject.meshSleep Apnea Syndromes
dc.titleValidity and Cost-Effectiveness of Pediatric Home Respiratory Polygraphy for the Diagnosis of Obstructive Sleep Apnea in Children: Rationale, Study Design, and Methodology
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.3390/mps4010009
dc.subject.decsanálisis coste-beneficio
dc.subject.decspolisomnografía
dc.subject.decsapnea obstructiva del sueño
dc.relation.publishversionhttps://www.mdpi.com/2409-9279/4/1/9
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Oceja E] Domiciliary Hospitalization, Sleep Unit, OSI Araba University Hospital, Vitoria, Spain. [Rodríguez P] Research Service and Bioaraba Research Institute, OSI Araba University Hospital, UPV/EHU, Vitoria, Spain. [Jurado MJ] Unitat del Son, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Luz Alonso M] Sleep Unit, Complejo Hospitalario de Burgos, Burgos, Spain. [Del Río G] Sleep Unit, Fundación Jiménez Díaz, Madrid, Spain. [Villar MÁ] Sleep Unit, Hospital Universitario de Basurto, Bilbao, Spain
dc.identifier.pmid33477929
dc.identifier.wos000636115700001
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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