dc.contributor | Vall d'Hebron Barcelona Hospital Campus |
dc.contributor.author | Diaz Riascos, Zamira Vanessa |
dc.contributor.author | Corchero Nieto, José Luis |
dc.contributor.author | González Callejo, Patricia |
dc.contributor.author | Garcia Aranda, Natalia |
dc.contributor.author | Mandaña Solé, Mònica |
dc.contributor.author | BOULLOSA GOBERNA, ANA MARIA |
dc.contributor.author | Mancilla-Zamora, Sandra |
dc.contributor.author | Grayston, Alba |
dc.contributor.author | Moltó Abad, Marc |
dc.contributor.author | Pintos-Morell, Guillem |
dc.contributor.author | Rosell Novel, Anna |
dc.contributor.author | Schwartz Navarro, Simon |
dc.contributor.author | Abasolo, Ibane |
dc.contributor.author | Seras-Franzoso, Joaquin |
dc.date.accessioned | 2021-07-27T11:03:33Z |
dc.date.available | 2021-07-27T11:03:33Z |
dc.date.issued | 2021-03 |
dc.identifier.citation | Seras‐Franzoso J, Díaz‐Riascos ZV, Corchero JL, González P, García‐Aranda N, Mandaña M, et al. Extracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders. J Extracell Vesicles. 2021 Mar;10(5):e12058. |
dc.identifier.issn | 2001-3078 |
dc.identifier.uri | https://hdl.handle.net/11351/6205 |
dc.description | N-sulfoglucosamina sulfohidrolasa; Teràpia de reemplaçament enzimàtic; Trastorns d’emmagatzematge lisosomal |
dc.description.sponsorship | This study has been supported by ISCIII (PI18_00871 co-founded by Fondo Europeo de Desarrollo Regional (FEDER)), and CIBER-BBN (EXPLORE) granted to IA. Different CIBER-BBN units of ICTS ‘NANBIOSIS’ have participated in this work (https://www.nanbiosis.es/platform-units/), more specifically the U1/Protein Production Platform for protein purification, Unit 6 for NTA analysis and TFF purification and U20/FVPR for in vivo assays. |
dc.language.iso | eng |
dc.publisher | Wiley |
dc.relation.ispartofseries | Journal of Extracellular Vesicles;10(5) |
dc.rights | Attribution 4.0 International |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ |
dc.source | Scientia |
dc.subject | Metabolisme - Trastorns |
dc.subject | Enzims extracel·lulars - Ús terapèutic |
dc.subject.mesh | Lysosomal Storage Diseases |
dc.subject.mesh | Extracellular Vesicles |
dc.subject.mesh | /enzymology |
dc.title | Extracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders |
dc.type | info:eu-repo/semantics/article |
dc.identifier.doi | 10.1002/jev2.12058 |
dc.subject.decs | enfermedades por almacenamiento lisosómico |
dc.subject.decs | vesículas extracelulares |
dc.subject.decs | /enzimología |
dc.relation.publishversion | https://onlinelibrary.wiley.com/doi/10.1002/jev2.12058 |
dc.type.version | info:eu-repo/semantics/publishedVersion |
dc.audience | Professionals |
dc.contributor.organismes | Institut Català de la Salut |
dc.contributor.authoraffiliation | [Seras-Franzoso J, González P, Schwartz S Jr] Drug Delivery & Targeting, CIBBIM-Nanomedicine, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Barcelona, Spain. [Díaz-Riascos ZV, García-Aranda N, Mandaña M, Boullosa A, Mancilla S, Abasolo I] Drug Delivery & Targeting, CIBBIM-Nanomedicine, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Barcelona, Spain. Functional Validation & Preclinical Research (FVPR), CIBBIM-Nanomedicine, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Corchero JL] Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Barcelona, Spain. Institut de Biotecnologia i de Biomedicina (IBB) and Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Grayston A, Rosell A] Neurovascular Research Laboratory, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Moltó-Abad M, Pintos-Morell G] Drug Delivery & Targeting, CIBBIM-Nanomedicine, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Division of Rare Diseases, Reference Center for Hereditary Metabolic Disorders (CSUR, XUEC, MetabERN, and CIBER-ER). Vall d’Hebron Hospital Universitari, Barcelona, Spain |
dc.identifier.pmid | 33738082 |
dc.identifier.wos | 000632839300005 |
dc.relation.projectid | info:eu-repo/grantAgreement/ES/PE2013-2016/PI18%2F00871 |
dc.rights.accessrights | info:eu-repo/semantics/openAccess |