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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorDiaz Riascos, Zamira Vanessa
dc.contributor.authorCorchero Nieto, José Luis
dc.contributor.authorGonzález Callejo, Patricia
dc.contributor.authorGarcia Aranda, Natalia
dc.contributor.authorMandaña Solé, Mònica
dc.contributor.authorBOULLOSA GOBERNA, ANA MARIA
dc.contributor.authorMancilla-Zamora, Sandra
dc.contributor.authorGrayston, Alba
dc.contributor.authorMoltó Abad, Marc
dc.contributor.authorPintos-Morell, Guillem
dc.contributor.authorRosell Novel, Anna
dc.contributor.authorSchwartz Navarro, Simon
dc.contributor.authorAbasolo, Ibane
dc.contributor.authorSeras-Franzoso, Joaquin
dc.date.accessioned2021-07-27T11:03:33Z
dc.date.available2021-07-27T11:03:33Z
dc.date.issued2021-03
dc.identifier.citationSeras‐Franzoso J, Díaz‐Riascos ZV, Corchero JL, González P, García‐Aranda N, Mandaña M, et al. Extracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders. J Extracell Vesicles. 2021 Mar;10(5):e12058.
dc.identifier.issn2001-3078
dc.identifier.urihttps://hdl.handle.net/11351/6205
dc.descriptionN-sulfoglucosamina sulfohidrolasa; Teràpia de reemplaçament enzimàtic; Trastorns d’emmagatzematge lisosomal
dc.description.sponsorshipThis study has been supported by ISCIII (PI18_00871 co-founded by Fondo Europeo de Desarrollo Regional (FEDER)), and CIBER-BBN (EXPLORE) granted to IA. Different CIBER-BBN units of ICTS ‘NANBIOSIS’ have participated in this work (https://www.nanbiosis.es/platform-units/), more specifically the U1/Protein Production Platform for protein purification, Unit 6 for NTA analysis and TFF purification and U20/FVPR for in vivo assays.
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofseriesJournal of Extracellular Vesicles;10(5)
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectMetabolisme - Trastorns
dc.subjectEnzims extracel·lulars - Ús terapèutic
dc.subject.meshLysosomal Storage Diseases
dc.subject.meshExtracellular Vesicles
dc.subject.mesh/enzymology
dc.titleExtracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1002/jev2.12058
dc.subject.decsenfermedades por almacenamiento lisosómico
dc.subject.decsvesículas extracelulares
dc.subject.decs/enzimología
dc.relation.publishversionhttps://onlinelibrary.wiley.com/doi/10.1002/jev2.12058
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Seras-Franzoso J, González P, Schwartz S Jr] Drug Delivery & Targeting, CIBBIM-Nanomedicine, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Barcelona, Spain. [Díaz-Riascos ZV, García-Aranda N, Mandaña M, Boullosa A, Mancilla S, Abasolo I] Drug Delivery & Targeting, CIBBIM-Nanomedicine, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Barcelona, Spain. Functional Validation & Preclinical Research (FVPR), CIBBIM-Nanomedicine, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Corchero JL] Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Barcelona, Spain. Institut de Biotecnologia i de Biomedicina (IBB) and Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Grayston A, Rosell A] Neurovascular Research Laboratory, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Moltó-Abad M, Pintos-Morell G] Drug Delivery & Targeting, CIBBIM-Nanomedicine, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Division of Rare Diseases, Reference Center for Hereditary Metabolic Disorders (CSUR, XUEC, MetabERN, and CIBER-ER). Vall d’Hebron Hospital Universitari, Barcelona, Spain
dc.identifier.pmid33738082
dc.identifier.wos000632839300005
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/PE2013-2016/PI18%2F00871
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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