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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorRodríguez Pardo, Ma Dolores
dc.contributor.authorEscola Verge, Laura
dc.contributor.authorSellares Nadal, Julia
dc.contributor.authorCorona Pérez-Cardona, Pablo Salvador
dc.contributor.authorAlmirante Gragera, Benito
dc.contributor.authorPigrau Serrallach, Carles
dc.date.accessioned2021-12-27T13:20:08Z
dc.date.available2021-12-27T13:20:08Z
dc.date.issued2021-04
dc.identifier.citationRodríguez-Pardo D, Escolà-Vergé L, Sellarès-Nadal J, Corona PS, Almirante B, Pigrau C. Periprosthetic Joint Infection Prophylaxis in the Elderly after Hip Hemiarthroplasty in Proximal Femur Fractures: Insights and Challenges. Antibiotics. 2021 Apr;10:429.
dc.identifier.issn2079-6382
dc.identifier.urihttp://hdl.handle.net/11351/6735
dc.descriptionAntibiotic prophylaxis; Hip hemiarthroplasty; Periprosthetic joint infection
dc.description.abstractWe review antibiotic and other prophylactic measures to prevent periprosthetic joint infection (PJI) after hip hemiarthroplasty (HHA) surgery in proximal femoral fractures (PFFs). In the absence of specific guidelines, those applied to these individuals are general prophylaxis guidelines. Cefazolin is the most widely used agent and is replaced by clindamycin or a glycopeptide in beta-lactam allergies. A personalized antibiotic scheme may be considered when colonization by a multidrug-resistant microorganism (MDRO) is suspected. Particularly in methicillin-resistant Staphylococcus aureus (MRSA) colonization or a high prevalence of MRSA-caused PJIs a glycopeptide with cefazolin is recommended. Strategies such as cutaneous decolonization of MDROs, mainly MRSA, or preoperative asymptomatic bacteriuria treatment have also been addressed with debatable results. Some areas of research are early detection protocols in MDRO colonizations by polymerase-chain-reaction (PCR), the use of alternative antimicrobial prophylaxis, and antibiotic-impregnated bone cement in HHA. Given that published evidence addressing PJI prophylactic strategies in PFFs requiring HHA is scarce, PJIs can be reduced by combining different prevention strategies after identifying individuals who will benefit from personalized prophylaxis.
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofseriesAntibiotics;10
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectArticulacions artificials
dc.subjectInfeccions quirúrgiques
dc.subjectMalalties bacterianes - Tractament
dc.subject.meshProsthesis-Related Infections
dc.subject.mesh/drug therapy
dc.subject.meshHemiarthroplasty
dc.subject.mesh/adverse effects
dc.titlePeriprosthetic Joint Infection Prophylaxis in the Elderly after Hip Hemiarthroplasty in Proximal Femur Fractures: Insights and Challenges
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.3390/antibiotics10040429
dc.subject.decsinfecciones relacionadas con prótesis
dc.subject.decs/farmacoterapia
dc.subject.decshemiartroplastia
dc.subject.decs/efectos adversos
dc.relation.publishversionhttps://doi.org/10.3390/antibiotics10040429
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Rodríguez-Pardo D] Servei de Malalties Infeccioses, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/0003), Instituto de Salud Carlos III, 28029 Madrid, Spain. Study Group on Osteoarticular Infections of the Spanish Society of Clinical Microbiology and Infectious Diseases (GEIO-SEIMC), 28003 Madrid, Spain. Medicina Interna, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Escolà-Vergé L, Pigrau C] Servei de Malalties Infeccioses, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/0003), Instituto de Salud Carlos III, 28029 Madrid, Spain. Study Group on Osteoarticular Infections of the Spanish Society of Clinical Microbiology and Infectious Diseases (GEIO-SEIMC), 28003 Madrid, Spain. [Sellarès-Nadal J] Servei de Malalties Infeccioses, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Study Group on Osteoarticular Infections of the Spanish Society of Clinical Microbiology and Infectious Diseases (GEIO-SEIMC), 28003 Madrid, Spain. Medicina Interna, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Corona PS] Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/0003), Instituto de Salud Carlos III, 28029 Madrid, Spain. Study Group on Osteoarticular Infections of the Spanish Society of Clinical Microbiology and Infectious Diseases (GEIO-SEIMC), 28003 Madrid, Spain. Medicina Interna, Universitat Autònoma de Barcelona, Bellaterra, Spain. Unitat de Cirurgia Sèptica i Reconstructiva (UCSO), Servei de Cirurgia Ortopèdica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Almirante B] Servei de Malalties Infeccioses, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/0003), Instituto de Salud Carlos III, 28029 Madrid, Spain. Medicina Interna, Universitat Autònoma de Barcelona, Bellaterra, Spain
dc.identifier.pmid33924353
dc.identifier.wos000642685100001
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/PE2013-2016/PI15%2F02161
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/PE2013-2016/RD16%2F0016%2F0003
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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