Show simple item record

 
dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorVergara Arana, Ander
dc.contributor.authorMolina Van den Bosch, Mireia
dc.contributor.authorToapanta Gaibor, Nestor Gabriel
dc.contributor.authorVillegas, Andrés
dc.contributor.authorSánchez-Cámara, Luis
dc.contributor.authorSoler Romeo, Maria Jose
dc.contributor.authorde Sequera, Patricia
dc.date.accessioned2022-01-31T10:49:32Z
dc.date.available2022-01-31T10:49:32Z
dc.date.issued2021-07-02
dc.identifier.citationVergara A, Molina-Van den Bosch M, Toapanta N, Villegas A, Sánchez-Cámara L, Sequera P, et al. The Impact of Age on Mortality in Chronic Haemodialysis Popu-Lation with COVID-19. J Clin Med. 2021 Jul 2;10(14):3022.
dc.identifier.issn2077-0383
dc.identifier.urihttps://hdl.handle.net/11351/6934
dc.descriptionCoronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Haemodialysis; Mortality
dc.description.abstractAge and chronic kidney disease have been described as mortality risk factors for coronavirus disease 2019 (COVID-19). Currently, an important percentage of patients in haemodialysis are elderly. Herein, we investigated the impact of age on mortality among haemodialysis patients with COVID-19. Data was obtained from the Spanish COVID-19 chronic kidney disease (CKD) Working Group Registry. From 18 March 2020 to 27 August 2020, 930 patients on haemodialysis affected by COVID-19 were included in the Registry. A total of 254 patients were under 65 years old and 676 were 65 years or older (elderly group). Mortality was 25.1% higher (95% CI: 22.2–28.0%) in the elderly as compared to the non-elderly group. Death from COVID-19 was increased 6.2-fold in haemodialysis patients as compared to the mortality in the general population in a similar time frame. In the multivariate Cox regression analysis, age (hazard ratio (HR) 1.59, 95% CI: 1.31–1.93), dyspnea at presentation (HR 1.51, 95% CI: 1.11–2.04), pneumonia (HR 1.74, 95% CI: 1.10–2.73) and admission to hospital (HR 4.00, 95% CI: 1.83–8.70) were identified as independent mortality risk factors in the elderly haemodialysis population. Treatment with glucocorticoids reduced the risk of death (HR 0.68, 95% CI: 0.48–0.96). In conclusion, mortality is dramatically increased in elderly haemodialysis patients with COVID-19. Our results suggest that this high risk population should be prioritized in terms of protection and vaccination.
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofseriesJournal of Clinical Medicine;10(14)
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectInsuficiència renal crònica - Tractament
dc.subjectHemodiàlisi
dc.subjectCOVID-19 (Malaltia) - Complicacions
dc.subject.meshRenal Insufficiency, Chronic
dc.subject.mesh/therapy
dc.subject.meshRenal Dialysis
dc.subject.meshAged
dc.subject.meshCoronavirus Infections
dc.titleThe Impact of Age on Mortality in Chronic Haemodialysis Population with COVID-19
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.3390/jcm10143022
dc.subject.decsinsuficiencia renal crónica
dc.subject.decs/terapia
dc.subject.decsdiálisis renal
dc.subject.decsanciano
dc.subject.decsinfecciones por Coronavirus
dc.relation.publishversionhttps://doi.org/10.3390/jcm10143022
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Vergara A, Toapanta N, Soler MJ] Servei de Nefrologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Nephrology Research Group, Vall d’Hebrón Research Institute, REDinREN, 08035 Barcelona, Spain. [Molina-Van den Bosch M] Nephrology Research Group, Vall d’Hebrón Research Institute, REDinREN, 08035 Barcelona, Spain. [Villegas A] Nephrology Department, Germans Trias i Pujol University Hospital, 08916 Badalona, Spain. [Sánchez-Cámara L] Nephrology Department, Fundación para la Investigación Biomédica Gregorio Marañón, 28007 Madrid, Spain. [Sequera P] Nephrology Department, Infanta Leonor University Hospital, 28031 Madrid, Spain
dc.identifier.pmid34300188
dc.identifier.wos000676583800001
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/PE2013-2016/RD16%2F0009%2F0030
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record