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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorPascal, Mariona
dc.contributor.authorMoreno, Carmen
dc.contributor.authorDávila, Ignacio
dc.contributor.authorTabar, Ana I.
dc.contributor.authorBartra, Joan
dc.contributor.authorLabrador Horrillo, Moisés
dc.contributor.authorLuengo Sanchez, Olga
dc.date.accessioned2022-03-31T10:32:09Z
dc.date.available2022-03-31T10:32:09Z
dc.date.issued2021-08
dc.identifier.citationPascal M, Moreno C, Dávila I, Tabar AI, Bartra J, Labrador M, et al. Integration of in vitro allergy test results and ratio analysis for the diagnosis and treatment of allergic patients (INTEGRA). Clin Transl Allergy. 2021 Aug;11(7):e12052.
dc.identifier.issn2045-7022
dc.identifier.urihttp://hdl.handle.net/11351/7287
dc.descriptionAllergy; Molecular diagnosis; Recommendations
dc.description.abstractThe introduction of molecular diagnosis into routine clinical practice has substantially improved the diagnosis and management of allergic patients by allowing clinicians to precisely identify the allergenic molecule responsible for immunoglobulin E (IgE)-mediated allergies. However, it can be challenging to accurately interpret the results of molecular assays, partly due to the limited evidence base. In this context, a panel of experts with extensive experience in interpreting in vitro measures of total and serum specific IgE reviewed the available scientific evidence. After this review, the panel selected a series of representative case studies to demonstrate how determination of specific and total IgE values and the relationship between them (ratio analysis) can add value to the diagnostic process by more precisely defining the patient’s sensitization profile. Finally, the experts developed a series of recommendations on the clinical application of ratio analysis to optimize and complement the classical approach to allergy diagnosis.
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofseriesClinical and Translational Allergy;11(7)
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectAl·lèrgia - Diagnòstic
dc.subjectDiagnòstic molecular
dc.subjectAl·lèrgia - Tractament
dc.subject.meshHypersensitivity
dc.subject.mesh/diagnosis
dc.subject.meshMolecular Diagnostic Techniques
dc.titleIntegration of in vitro allergy test results and ratio analysis for the diagnosis and treatment of allergic patients (INTEGRA)
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1002/clt2.12052
dc.subject.decshipersensibilidad
dc.subject.decs/diagnóstico
dc.subject.decstécnicas de diagnóstico molecular
dc.relation.publishversionhttps://doi.org/10.1002/clt2.12052
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Pascal M] Immunology Department, Centre de Diagnòstic Biomèdic, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain. ARADyAL Network, Health Institute Carlos III, Madrid, Spain. [Moreno C] ARADyAL Network, Health Institute Carlos III, Madrid, Spain. Allergy Service, Hospital Universitario Reina Sofía, Maimonides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain. [Dávila I] ARADyAL Network, Health Institute Carlos III, Madrid, Spain. Allergy Service, Department of Biomedical and Diagnostic Sciences and Institute for Biomedical Research of Salamanca (IBSAL), University Hospital of Salamanca, Salamanca, Spain. [Tabar AI] ARADyAL Network, Health Institute Carlos III, Madrid, Spain. Allergy Service, Hospital Complex of Navarra, Pamplona, Spain. Navarra Institute for Health Research (IdiSNA), Cooperative Health Research Thematic Networks (RETICs) for Asthma, Madrid, Spain. [Bartra J] ARADyAL Network, Health Institute Carlos III, Madrid, Spain. Allergy Section, Pneumology Department, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain. [Labrador M, Luengo O] ARADyAL Network, Health Institute Carlos III, Madrid, Spain. Secció d’Al·lèrgia, Servei de Medicina Interna, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain
dc.identifier.pmid34582103
dc.identifier.wos000700512700002
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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