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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorDíez, Juan J.
dc.contributor.authorAlcázar, Victoria
dc.contributor.authorIglesias, Pedro
dc.contributor.authorRomero-Lluch, Ana
dc.contributor.authorSastre, Julia
dc.contributor.authorPérez Corral, Begoña
dc.contributor.authorZafon, Carles
dc.date.accessioned2022-04-06T12:13:43Z
dc.date.available2022-04-06T12:13:43Z
dc.date.issued2021-02
dc.identifier.citationDíez JJ, Alcázar V, Iglesias P, Romero-Lluch A, Sastre J, Corral BP, et al. Thyroid lobectomy in patients with differentiated thyroid cancer: an analysis of the clinical outcomes in a nationwide multicenter study. Gland Surg. 2021 Feb;10(2):678–89.
dc.identifier.issn2227-8575
dc.identifier.urihttp://hdl.handle.net/11351/7319
dc.descriptionThyroid surgery; Lobectomy; Tumor recurrence
dc.description.abstractBackground: Total thyroidectomy is the standard initial surgery for differentiated thyroid carcinoma (DTC), but the extent of the thyroidectomy remains controversial. Thyroid lobectomy (TL) has been widely used in eastern countries; however, its use has not been generalized in western countries, including Spain. Our aims were to analyse the clinical outcome of a multicentre nation-wide cohort of DTC patients treated by TL and to assess the proportion of patients who required completion of the thyroidectomy and who presented disease recurrence. Methods: We retrospectively analyzed patients who underwent TL for DTC and were followed-up for ≥12 months. We collected demographic, clinical, and histopathological data. Dynamic risk stratification (DRS) was performed at 12 months and at last visit. Results: One hundred and sixty-four patients (128 women, mean age 50.8 years, median follow-up 45.4 months) from 9 hospitals were included. There were 158 cases of papillary and 6 of follicular thyroid carcinoma (FTC). Remission of the disease (excellent response) was shown in 71.6% of the patients at 12 months and in 74.4% at the end of follow-up. At that time, there were 34 patients (20.7%) with indeterminate response, 6 (3.7%) with biochemical incomplete response, and 2 (1.2%) with structural incomplete response. Completion of the thyroidectomy was necessary in 8 patients (4.9%), but only 3 of them (1.8%) had disease recurrence. Conclusions: These results, obtained in real clinical practice, suggest that TL is a safe operative option for selected patients with DTC and that the intensity of the treatment must be tailored according to the presurgical tumor-associated risk, in line with a personalized medicine.
dc.language.isoeng
dc.publisherAME Publishing Company
dc.relation.ispartofseriesGland Surgery;10(2)
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceScientia
dc.subjectTiroide - Càncer - Cirurgia
dc.subjectTiroïdectomia
dc.subjectAvaluació de resultats (Assistència sanitària)
dc.subject.meshThyroid Neoplasms
dc.subject.mesh/surgery
dc.subject.meshThyroidectomy
dc.subject.meshTreatment Outcome
dc.titleThyroid lobectomy in patients with differentiated thyroid cancer: an analysis of the clinical outcomes in a nationwide multicenter study
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.21037/gs-20-712
dc.subject.decsneoplasias de la tiroides
dc.subject.decs/cirugía
dc.subject.decstiroidectomía
dc.subject.decsresultado del tratamiento
dc.relation.publishversionhttp://dx.doi.org/10.21037/gs-20-712
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Díez JJ, Iglesias P] Department of Endocrinology, Hospital Universitario Ramón y Cajal, Madrid, Spain. Department of Endocrinology, Hospital Universitario Puerta de Hierro Majadahonda, Instituto de Investigación Sanitaria Puerta de Hierro Segovia de Arana, Majadahonda, Madrid, Spain. [Alcázar V] Department of Endocrinology, Hospital Universitario Severo Ochoa, Leganés, Madrid, Spain. [Romero-Lluch A] Department of Endocrinology, Hospital Universitario Virgen del Rocío, Sevilla, Spain. [Sastre J] Department of Endocrinology, Complejo Hospitalario de Toledo, Toledo, Spain. [Corral BP] Department of Endocrinology, Complejo Asistencial Universitario de León, León, Spain. [Zafón C] Servei d’Endocrinologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain
dc.identifier.pmid33708550
dc.identifier.wos000622479000017
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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