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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorMontes de Oca, Maria
dc.contributor.authorLopez Varela, Maria Victorina
dc.contributor.authorMenezes, Ana M. B.
dc.contributor.authorWehrmeister, Fernando C.
dc.contributor.authorRamirez, Larissa
dc.contributor.authorMiravitlles Fernández, Marc
dc.date.accessioned2022-05-13T05:57:58Z
dc.date.available2022-05-13T05:57:58Z
dc.date.issued2021
dc.identifier.citationMontes de Oca M, Lopez Varela MV, Menezes AMB, Wehrmeister FC, Ramirez L, Miravitlles M. Respiratory symptoms (COPD Assessment Test and modified Medical Research Council dyspnea scores) and GOLD-ABCD COPD classification: the LASSYC study. J Bras Pneumol. 2021;47(5):e20210156.
dc.identifier.issn1806-3756
dc.identifier.urihttp://hdl.handle.net/11351/7521
dc.descriptionChronic obstructive pulmonary disease; Symptoms; COPD
dc.description.abstractObjective To assess the frequency and severity of 24-hour respiratory symptoms according to COPD GOLD-ABCD classification (2017-version), the distribution of the patients with COPD into GOLD categories using mMRC (≥2) or CAT (≥10) scores, and agreement between these cut-off points. Methods In this cross-sectional study (LASSYC study), 24-hour day respiratory symptoms were assessed by the Evaluating Respiratory Symptoms in COPD (E-RS) questionnaire, Nighttime Symptoms of COPD Instrument (NiSCI), Early Morning Symptoms of COPD Instrument (EMSCI), CAT and mMRC scores. Results Among the 734 patients with COPD, 61% were male, age 69.6±8.7 years, FEV1% post-BD 49.1±17.5%, mMRC 1.8±1.0 and CAT 15.3±.8.1. By mMRC 33.7% were group-A, 29.2% group-B, 10.2% group-C and 26.9% group-D. By CAT 22.3% were group-A, 41% group-B, 4.8% group-C and 31.9% group-D. Using the mMRC the severity of E-RS, NiSCI and EMSCI scores increased from group A to D. Using the CAT, the groups B and D had the higher scores. Agreement between mMRC and CAT was 89.5% (Kappa statistics=75.7%). For mMRC score of 2, CAT score of ≥11 showed the maximum Youden’s index (1.34). For mMRC score of 1, CAT score of ≥9 and ≥10 showed the maximum Youden’s index (1.48). Conclusion GOLD COPD classification by CAT seems to better discriminate 24-hour symptoms. Results do not support the equivalent use of CAT≥10 and mMRC≥2 for assessing symptoms.
dc.language.isoeng
dc.publisherSociedade Brasileira de Pneumologia e Tisiologia
dc.relation.ispartofseriesJornal Brasileiro de Pneumologia;47(5)
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.sourceScientia
dc.subjectQüestionaris
dc.subjectPulmons - Malalties obstructives - Diagnòstic
dc.subject.meshPulmonary Disease, Chronic Obstructive
dc.subject.mesh/diagnosis
dc.subject.meshSurveys and Questionnaires
dc.titleRespiratory symptoms (COPD Assessment Test and modified Medical Research Council dyspnea scores) and GOLD-ABCD COPD classification: the LASSYC study
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.36416/1806-3756/e20210156
dc.subject.decsenfermedad pulmonar obstructiva crónica
dc.subject.decs/diagnóstico
dc.subject.decsencuestas y cuestionarios
dc.relation.publishversionhttps://doi.org/10.36416/1806-3756/e20210156
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Montes de Oca M] Universidad Central de Venezuela, Caracas, Venezuela. [Lopez Varela MV] Universidad de la República, Montevideo, Uruguay. [Menezes AMB, Wehrmeister FC] Programa de Pós-graduação em Epidemiologia, Universidade Federal de Pelotas, Pelotas (RS) Brasil. [Ramirez L] AstraZeneca, Costa Rica. [Miravitlles M] Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBER de Enfermedades Respiratorias, Barcelona, Spain
dc.identifier.pmid34787288
dc.identifier.wos000755715900007
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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