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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorMuñoz, Gerard
dc.contributor.authorGracia Roldán, Javier de
dc.contributor.authorGiron, Rosa
dc.contributor.authorOlveira Fuster, Casilda
dc.contributor.authorÁlvarez Fernandez, Antonio
dc.contributor.authorBuxó, Maria
dc.date.accessioned2022-05-30T13:19:55Z
dc.date.available2022-05-30T13:19:55Z
dc.date.issued2021-01-01
dc.identifier.citationMuñoz G, de Gracia J, Giron R, Olveira C, Alvarez A, Buxó M, et al. Validation of a Spanish version of the Leicester Cough Questionnaire in cystic fibrosis. Chron Respir Dis. 2021 Jan 1;18:1–8.
dc.identifier.issn1479-9731
dc.identifier.urihttp://hdl.handle.net/11351/7582
dc.descriptionBronchiectasis; Quality of life; Respiratory disease
dc.description.abstractCough is a main symptom in cystic fibrosis (CF). We aim to validate a Spanish version of the Leicester Cough Questionnaire (LCQ-Sp) to measure the impact of cough in CF bronchiectasis. A prospective longitudinal multicentre study was performed. Internal consistency and score changes over a 15-day period in stable state were assessed to analyse reliability. Concurrent validity was analysed by correlation with Saint George’s Respiratory Questionnaire (SGRQ) and convergent validity by assessing the association with clinical variables. Changes in scores between stable state and the first exacerbation were assessed to analyse responsiveness. 132 patients (29.73 ± 10.52 years) were enrolled in four hospitals. Internal consistency was high for the total score and good for the three domains (Cronbach’s α 0.81–0.93). The test–retest reliability showed an intraclass correlation coefficient of 0.86 for the total score. The correlation between LCQ-Sp and SGRQ scores was −0.74. The LCQ-Sp score negatively correlated with sputum volume, and the mean score decreased at the beginning of exacerbations (16.04±3.81 vs 13.91±4.29) with a large effect size. The LCQ-Sp is a reliable, repeatable and responsive instrument to assess the impact of cough in CF bronchiectasis and is responsive to change in the event of exacerbations.
dc.language.isoeng
dc.publisherSAGE Publications
dc.relation.ispartofseriesChronic Respiratory Disease;18
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.sourceScientia
dc.subjectQüestionaris
dc.subjectFibrosi pulmonar - Complicacions
dc.subjectTos
dc.subject.meshSurveys and Questionnaires
dc.subject.meshCystic Fibrosis
dc.subject.mesh/complications
dc.subject.meshCough
dc.titleValidation of a Spanish version of the Leicester Cough Questionnaire in cystic fibrosis
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1177/14799731211036903
dc.subject.decsencuestas y cuestionarios
dc.subject.decsfibrosis quística
dc.subject.decs/complicaciones
dc.subject.decstos
dc.relation.publishversionhttps://doi.org/10.1177/14799731211036903
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Muñoz G] Respiratory Group, Girona Biomedical Research Institute [IDIBGI], Girona, Spain. Departament of Physical Therapy, EUSES, Girona, Spain. [de Gracia J, Alvarez A] CIBER of Respiratory Diseases (Ciberes CB06/06/0030), Carlos III Health Institute, Madrid, Spain. Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Giron R] Department of Respiratory Medicine, Instituto de Investigación del Hospital de la Princesa, Madrid, Spain. [Olveira C] Department of Respiratory Medicine, Malaga Regional University Hospital, Instituto de Biomedicina de Málaga (IBIMA), Universidad de Málaga, Málaga, Spain. [Alvarez A] CIBER of Respiratory Diseases (Ciberes CB06/06/0030), Carlos III Health Institute, Madrid, Spain. Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Buxó M] Girona Biomedical Research Institute [IDIBGI], Girona, Spain
dc.identifier.pmid34730449
dc.identifier.wos000715821800001
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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