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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorGonzález-Martínez, Silvia
dc.contributor.authorPizarro, David
dc.contributor.authorPérez-Mies, Belén
dc.contributor.authorCaniego-Casas, Tamara
dc.contributor.authorCurigliano, Giuseppe
dc.contributor.authorCortés Castan, Javier
dc.contributor.authorPalacios, José
dc.date.accessioned2022-06-07T07:58:39Z
dc.date.available2022-06-07T07:58:39Z
dc.date.issued2021-10-28
dc.identifier.citationGonzález-Martínez S, Pizarro D, Pérez-Mies B, Caniego-Casas T, Curigliano G, Cortés J, et al. Clinical, Pathological, and Molecular Features of Breast Carcinoma Cutaneous Metastasis. Cancers. 2021 Oct 28;13(21):5416.
dc.identifier.issn2072-6694
dc.identifier.urihttp://hdl.handle.net/11351/7630
dc.descriptionBreast cancer; Metastasis; Skin
dc.description.abstractCutaneous metastases (CMs) account for 2% of all skin malignancies, and nearly 70% of CMs in women originate from breast cancer (BC). CMs are usually associated with poor prognosis, are difficult to treat, and can pose diagnostic problems, such as in histopathological diagnosis when occurring long after development of the primary tumor. In addition, the molecular differences between the primary tumors and their CMs, and between CMs and metastases in other organs, are not well defined. Here, we review the main clinical, pathological, and molecular characteristics of breast cancer CMs. Identifying molecular markers in primary BC that predict CM and can be used to determine the molecular differences between primary tumors and their metastases is of great interest for the design of new therapeutic approaches.
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofseriesCancers;13(21)
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectMama - Càncer - Prognosis
dc.subjectMetàstasi
dc.subjectCèl·lules canceroses - Proliferació
dc.subject.meshBreast Neoplasms
dc.subject.meshNeoplasm Metastasis
dc.subject.mesh/pathology
dc.titleClinical, Pathological, and Molecular Features of Breast Carcinoma Cutaneous Metastasis
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.3390/cancers13215416
dc.subject.decsneoplasias de la mama
dc.subject.decsmetástasis neoplásica
dc.subject.decs/patología
dc.relation.publishversionhttps://doi.org/10.3390/cancers13215416
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[González-Martínez S] Clinical Researcher, Hospital Ramón y Cajal, Madrid, Spain. Fundación Contigo contra el Cáncer de la Mujer, Madrid, Spain. [Pizarro D, Caniego-Casas T] Department of Pathology, Hospital Ramón y Cajal, Madrid, Spain. [Pérez-Mies B, Palacios J] Department of Pathology, Hospital Ramón y Cajal, Madrid, Spain. Institute Ramón y Cajal for Health Research (IRYCIS), Madrid, Spain. CIBER-ONC, Instituto de Salud Carlos III, Madrid, Spain. Faculty of Medicine, University of Alcalá de Henares, Alcalá de Henares, Madrid, Spain. [Curigliano G] European Institute of Oncology, IRCCS, Milan, Italy. Departament of Oncology and Hematology, University of Milan, Milan, Italy. [Cortés J] CIBER-ONC, Instituto de Salud Carlos III, Madrid, Spain. Department of Medicine, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain. Department of Medicine, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain. International Breast Cancer Center (IBCC), Quironsalud Group, Barcelona, Spain. Medica Scientia Innovation Research, Barcelona, Spain. Medica Scientia Innovation Research, Ridgewood, NJ, USA. Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain
dc.identifier.pmid34771579
dc.identifier.wos000719073300001
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/PE2013-2016/CB16%2F12%2F00449
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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