Modeling iPSC-derived human neurofibroma-like tumors in mice uncovers the heterogeneity of Schwann cells within plexiform neurofibromas

Mazuelas, Helena; Fernández-Rodríguez, Juana; Uriarte-Arrazola, Itziar; Richaud-Patin, Yvonne; Terribas, Ernest; Romagosa Pérez-Portabell, Cleofé; Magallon-Lorenz, Miriam

dc.contributor	Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author	Mazuelas, Helena
dc.contributor.author	Fernández-Rodríguez, Juana
dc.contributor.author	Uriarte-Arrazola, Itziar
dc.contributor.author	Richaud-Patin, Yvonne
dc.contributor.author	Terribas, Ernest
dc.contributor.author	Romagosa Pérez-Portabell, Cleofé
dc.contributor.author	Magallon-Lorenz, Miriam
dc.date.accessioned	2022-07-19T11:57:05Z
dc.date.available	2022-07-19T11:57:05Z
dc.date.issued	2022-02-15
dc.identifier.citation	Mazuelas H, Magallón-Lorenz M, Fernández-Rodríguez J, Uriarte-Arrazola I, Richaud-Patin Y, Terribas E, et al. Modeling iPSC-derived human neurofibroma-like tumors in mice uncovers the heterogeneity of Schwann cells within plexiform neurofibromas. Cell Rep. 2022 Feb 15;38(7):110385.
dc.identifier.issn	2211-1247
dc.identifier.uri	https://hdl.handle.net/11351/7831
dc.description	Fibroblast; Cresta neural; Esferoides
dc.description.sponsorship	This work has mainly been supported by an agreement from the Johns Hopkins University School of Medicine and the Neurofibromatosis Therapeutic Acceleration Program (NTAP). Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Johns Hopkins University School of Medicine. The work has also been partially supported by the Spanish Ministry of Science and Innovation, Carlos III Health Institute (ISCIII) (PI17/00524; PI20/00228) Plan Estatal de I + D + I 2013–2016, co-financed by the FEDER program – a way to build Europe, the Fundación PROYECTO NEUROFIBROMATOSIS, and by the Government of Catalonia (2017-SGR-496) and CERCA Program/Generalitat de Catalunya. M.M.-L. is supported by Fundación PROYECTO NEUROFIBROMATOSIS.
dc.language.iso	eng
dc.publisher	Cell Press
dc.relation.ispartofseries	Cell Reports;38(7)
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.source	Scientia
dc.subject	Ratolins
dc.subject	Teixit nerviós - Tumors
dc.subject.mesh	Neurofibroma, Plexiform
dc.title	Modeling iPSC-derived human neurofibroma-like tumors in mice uncovers the heterogeneity of Schwann cells within plexiform neurofibromas
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	10.1016/j.celrep.2022.110385
dc.subject.decs	neurofibroma plexiforme
dc.relation.publishversion	https://doi.org/10.1016/j.celrep.2022.110385
dc.type.version	info:eu-repo/semantics/publishedVersion
dc.audience	Professionals
dc.contributor.organismes	Institut Català de la Salut
dc.contributor.authoraffiliation	[Mazuelas H, Magallón-Lorenz M, Uriarte-Arrazola I] Hereditary Cancer Group, Germans Trias i Pujol Research Institute (IGTP), Can Ruti Campus, Badalona, Spain. [Fernández-Rodríguez J] Hereditary Cancer Program, Catalan Institute of Oncology (ICO-IDIBELL), L’Hospitalet de Llobregat, Spain. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. [Richaud-Patin Y] Regenerative Medicine Program, Bellvitge Institute for Biomedical Research (IDIBELL) and Program for Clinical Translation of Regenerative Medicine in Catalonia (P-CMRC), L’Hospitalet de Llobregat, Spain. Center for Networked Biomedical Research on Bioengineering, Biomaterials, and Nanomedicine (CIBER-BBN), Madrid, Spain. [Terribas E] Hereditary Cancer Group, Germans Trias i Pujol Research Institute (IGTP), Can Ruti Campus, Badalona, Spain. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. [Romagosa C] Servei de Patologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBERONC, Barcelona, Spain. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain
dc.identifier.pmid	35172160
dc.identifier.wos	000759190300002
dc.rights.accessrights	info:eu-repo/semantics/openAccess