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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorRuiz Muñoz, Aroa
dc.contributor.authorGuala, Andrea
dc.contributor.authorDux-Santoy Hurtado, Lydia
dc.contributor.authorTeixido Tura, Gisela
dc.contributor.authorServato, Maria Luz
dc.contributor.authorDe Carvalho Negrao Valente, Filipa Xavier
dc.contributor.authorGarrido Oliver, Juan
dc.contributor.authorGalián Gay, Laura
dc.contributor.authorGutierrez García-Moreno, Laura
dc.contributor.authorFernández Galera, Ruben
dc.contributor.authorCasas Masnou, Guillem
dc.contributor.authorGonzález Alujas, Teresa
dc.contributor.authorCuellar Calabria, Hug
dc.contributor.authorFerreira González, Ignacio
dc.contributor.authorEvangelista Masip, Artur
dc.contributor.authorRodríguez Palomares, Jose Fernando
dc.date.accessioned2022-08-12T09:52:38Z
dc.date.available2022-08-12T09:52:38Z
dc.date.issued2022-03-28
dc.identifier.citationRuiz-Muñoz A, Guala A, Dux-Santoy L, Teixidó-Turà G, Servato ML, Valente F, et al. False lumen rotational flow and aortic stiffness are associated with aortic growth rate in patients with chronic aortic dissection of the descending aorta: a 4D flow cardiovascular magnetic resonance study. J Cardiovasc Magn Reson. 2022 Mar 28;24:20.
dc.identifier.issn1532-429X
dc.identifier.urihttp://hdl.handle.net/11351/7998
dc.descriptionAortic dissection; Aortic stiffness; Magnetic resonance imaging
dc.description.abstractBackground Patency of the false lumen in chronic aortic dissection (AD) is associated with aortic dilation and long-term aortic events. However, predictors of adverse outcomes in this population are limited. The aim of this study was to evaluate the relationship between aortic growth rate and false lumen flow dynamics and biomechanics in patients with chronic, patent AD. Methods Patients with a chronic AD with patent false lumen in the descending aorta and no genetic connective tissue disorder underwent an imaging follow-up including a contrast-enhanced 4D flow cardiovascular magnetic resonance (CMR) protocol and two consecutive computed tomography angiograms (CTA) acquired at least 1 year apart. A comprehensive analysis of anatomical features (including thrombus quantification), and false lumen flow dynamics and biomechanics (pulse wave velocity) was performed. Results Fifty-four consecutive patients with a chronic, patent false lumen in the descending aorta were included (35 surgically-treated type A AD with residual tear and 19 medically-treated type B AD). Median follow-up was 40 months. The in-plane rotational flow, pulse wave velocity and the percentage of thrombus in the false lumen were positively related to aortic growth rate (p = 0.006, 0.017, and 0.037, respectively), whereas wall shear stress showed a trend for a positive association (p = 0.060). These results were found irrespectively of the type of AD. Conclusions In patients with chronic AD and patent false lumen of the descending aorta, rotational flow, pulse wave velocity and wall shear stress are positively related to aortic growth rate, and should be implemented in the follow-up algorithm of these patients. Further prospective studies are needed to confirm if the assessment of these parameters helps to identify patients at higher risk of adverse clinical events.
dc.language.isoeng
dc.publisherBMC
dc.relation.ispartofseriesJournal of Cardiovascular Magnetic Resonance;24
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectAneurismes aòrtics
dc.subjectCor - Malalties - Imatgeria per ressonància magnètica
dc.subject.meshAneurysm, Dissecting
dc.subject.mesh/diagnostic imaging
dc.subject.meshAortic Aneurysm, Thoracic
dc.titleFalse lumen rotational flow and aortic stiffness are associated with aortic growth rate in patients with chronic aortic dissection of the descending aorta: a 4D flow cardiovascular magnetic resonance study
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1186/s12968-022-00852-6
dc.subject.decsaneurisma disecante
dc.subject.decs/diagnóstico por imagen
dc.subject.decsaneurisma de la aorta torácica
dc.relation.publishversionhttps://doi.org/10.1186/s12968-022-00852-6
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Ruiz-Muñoz A, Rodriguez-Palomares J] Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBER-CV, Instituto de Salud Carlos III, Madrid, Spain. Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Guala A] Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBER-CV, Instituto de Salud Carlos III, Madrid, Spain. [Dux-Santoy L, Garrido-Oliver J] Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Teixidó-Turà G] Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBER-CV, Instituto de Salud Carlos III, Madrid, Spain. Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Servato ML, Valente F, Gay L, Gutiérrez L, Fernandez-Galera R, Casas G, González-Alujas T] Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Cuéllar-Calabria H] Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Servei de Radiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Ferreira-Gonzalez I] Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. CIBERESP, Instituto de Salud Carlos III, Madrid, Spain. [Evangelista A] Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBER-CV, Instituto de Salud Carlos III, Madrid, Spain. Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Instituto del Corazón. QuirónsaludTeknon, Barcelona, Spain
dc.identifier.pmid35346239
dc.identifier.wos000773932300002
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/PE2013-2016/PI17%2F00381
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/PE2017-2020/PI20%2F01727
dc.relation.projectidinfo:eu-repo/grantAgreement/ES/PE2013-2016/IJC2018-037349-I
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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