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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorMayoral, Karina
dc.contributor.authorGarin, Olatz
dc.contributor.authorLizano‑Barrantes, Catalina
dc.contributor.authorPont, Angels
dc.contributor.authorCaballero‑Rabasco, Araceli M.
dc.contributor.authorPraena‑Crespo, Manuel
dc.contributor.authorde Mir Messa, Inés
dc.date.accessioned2022-08-12T12:45:23Z
dc.date.available2022-08-12T12:45:23Z
dc.date.issued2022-03-28
dc.identifier.citationMayoral K, Garin O, Lizano-Barrantes C, Pont A, Caballero-Rabasco AM, Praena-Crespo M, et al. Measurement properties of the EQ-5D-Y administered through a smartphone app in children with asthma: a longitudinal questionnaire study. Health Qual Life Outcomes. 2022 Mar 28;20:51.
dc.identifier.issn1477-7525
dc.identifier.urihttp://hdl.handle.net/11351/8002
dc.descriptionHealth-related quality of life; Asthma; Smartphone app
dc.description.abstractBackground Asthma impacts children’s physical, emotional, and psychosocial Health-Related Quality of Life (HRQL). The EQ-5D-Y is a generic econometric instrument developed to measure HRQL in children. Objective Evaluation of feasibility, validity, reliability, and responsiveness of EQ-5D-Y descriptive system and utility index to allow the assessment of HRQL in children with asthma, aged 8–11 years (self-response version) or under 8 years old (proxy-response version). Methods We used data from baseline to 10 months of follow-up of an observational, prospective study of children with persistent asthma recruited by pediatricians in Spain (2018–2020). HRQL instruments were administered through a smartphone application: ARCA app. The EQ-5D-Y is composed of a 5-dimension descriptive system, a utility index ranging from 1 to − 0.5392, and a general health visual analogue scale (EQ-VAS). The Pediatric Asthma Impact Scale (PROMIS-PAIS) includes 8 items, providing a raw score. Construct validity hypotheses were stated a priori, and evaluated following two approaches, multitrait–multimethod matrix and known groups’ comparisons. Reliability and responsiveness subsamples were defined by stability or change in EQ-VAS and the Asthma Control Questionnaire (ACQ), to estimate the intraclass correlation coefficient (ICC) and the magnitude of change over time. Results The EQ-5D-Y was completed at baseline for 119 children (81 self-responded and 38 through proxy response), with a mean age of 9.1 (1.7) years. Mean (SD) of the EQ-5D-Y utility index was 0.93 (0.11), with ceiling and floor effects of 60.3% and 0%, respectively. Multitrait–multimethod matrix confirmed the associations previously hypothesized for the EQ-5D-Y utility index [moderate with PROMIS-PAIS (0.38) and weak with ACQ (0.28)], and for the EQ-5D-Y dimension “problems doing usual activities” [moderate with the ACQ item (0.35) and weak with the PROMIS-PAIS item (0.17)]. Statistically significant differences were found in the EQ-5D-Y between groups defined by asthma control, reliever inhalers use, and second-hand smoke exposure, with mostly moderate effect sizes (0.45–0.75). The ICC of the EQ-5D-Y utility index in the stable subsamples was high (0.81 and 0.79); and responsiveness subsamples presented a moderate to large magnitude of change (0.68 and 0.78), though without statistical significance. Conclusions These results support the use of the EQ-5D-Y as a feasible, valid, and reliable instrument for evaluating HRQL in children with persistent asthma. Further studies are needed on the responsiveness of the EQ-5D-Y in this population.
dc.language.isoeng
dc.publisherBMC
dc.relation.ispartofseriesHealth and Quality of Life Outcomes;20
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectAsma
dc.subjectAplicacions mòbils
dc.subjectQüestionaris
dc.subject.meshSurveys and Questionnaires
dc.subject.meshMobile Applications
dc.subject.meshAsthma
dc.titleMeasurement properties of the EQ-5D-Y administered through a smartphone app in children with asthma: a longitudinal questionnaire study
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1186/s12955-022-01955-5
dc.subject.decsencuestas y cuestionarios
dc.subject.decsaplicaciones en aparatos electrónicos portátiles
dc.subject.decsasma
dc.relation.publishversionhttps://doi.org/10.1186/s12955-022-01955-5
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Mayoral K] Health Service Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona Biomedical Research Park, Barcelona, Spain. Departament de Pediatria, Obstetrícia i Ginecologia, Departament de Medicina Preventiva, Universitat Autònoma de Barcelona, Bellaterra, Spain. CIBER en Epidemiología y Salud Pública, CIBERESP, Madrid, Spain. [Garin O] Health Service Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona Biomedical Research Park, Barcelona, Spain. CIBER en Epidemiología y Salud Pública, CIBERESP, Madrid, Spain. Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain. [Lizano-Barrantes C] Health Service Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona Biomedical Research Park, Barcelona, Spain. Department of Pharmaceutical Care and Clinical Pharmacy, Faculty of Pharmacy, Universidad de Costa Rica, San José, Costa Rica. Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain. [Pont A] Health Service Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona Biomedical Research Park, Barcelona, Spain. CIBER en Epidemiología y Salud Pública, CIBERESP, Madrid, Spain. [Caballero-Rabasco AM] Paediatric Pulmonology and Allergy Unit, Paediatric Department, Hospital Del Mar, Barcelona, Spain. Departament de Pediatria, Obstetrícia i Ginecologia, Departament de Medicina Preventiva, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Praena-Crespo M] Centro de Salud La Candelaria. Servicio Andaluz de Salud, Sevilla, Spain. Grupo de Vías Respiratorias de La Asociación Española de Pediatras de Atención Primaria (AEPAP), Madrid, Spain.[Mir I] Vall d’Hebron Hospital Universitari, Barcelona, Spain
dc.identifier.pmid35346225
dc.identifier.wos000773936700004
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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