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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorFernandez-Rodriguez, Lissett Jeanette
dc.contributor.authorArens-Benites, María Alejandra
dc.contributor.authorMaldonado Pijoan, Javier
dc.date.accessioned2022-08-16T06:53:23Z
dc.date.available2022-08-16T06:53:23Z
dc.date.issued2022-02-24
dc.identifier.citationFernández-Rodríguez LJ, Arens-Benites MA, Maldonado-Pijoan X. Image-Guided Radiation Therapy for Squamous Cell Cancer of the Head and Neck in a Specialized Peruvian Public Hospital. Cureus. 2022 Feb 24;14(2):e22569.
dc.identifier.issn2168-8184
dc.identifier.urihttp://hdl.handle.net/11351/8006
dc.descriptionHead and neck cancer; Image guided radiotherapy; Squamous cell cancer
dc.description.abstractSquamous cell cancer of the head and neck (SCCHN) often requires adjuvant radiotherapy. Radiotherapy for SCCHN is a challenge because the head and neck contain several critical organs that should receive minimal doses of radiation. These organs include the eyes, parotid glands, brainstem, spinal cord, mandible, and thyroid gland. Approaches like image-guided radiotherapy (IGRT) combined with volumetric modulated arc therapy hold the promise to focus radiation to the planning target volume and spare nearby structures while observing potential changes to patient anatomy during treatment to determine whether replanning is required. IGRT, however, requires the frequent imaging of patients to update the treatment plan. In this retrospective study, we present our findings of SCCHN patients treated in a public hospital in Peru. The patients reflected overall demographic trends associated with SCCHN. Each patient was imaged using computed tomography once before radiotherapy and once by cone-beam computed tomography (CBCT) during treatment, for a total of two images. Tumor displacement, planning target volume, gross tumor volume, and neck diameter were compared between the two images. Among the measurements, only a small statistically significant increase in gross tumor volume was observed between the images. However, a minority of patients did experience changes to anatomy, which highlights the need for continued research into criteria to determine which patients are likely to benefit from treatment replanning due to intra-treatment anatomical changes. Alternatively, a lack of frequent CBCT imaging before each session, due to high patient flows and limited staff resources, made it difficult to observe transient changes and trends in each patient. We conclude that the treatment and outcome improvements associated with IGRT are likely associated with frequent imaging during radiotherapy and properly selecting which patients will benefit most from this resource-intensive technique.
dc.language.isoeng
dc.publisherCureus
dc.relation.ispartofseriesCureus;14(2)
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectCap - Càncer - Radioteràpia
dc.subjectColl - Càncer - Radioteràpia
dc.subject.meshSquamous Cell Carcinoma of Head and Neck
dc.subject.mesh/radiotherapy
dc.subject.meshRadiotherapy, Image-Guided
dc.titleImage-Guided Radiation Therapy for Squamous Cell Cancer of the Head and Neck in a Specialized Peruvian Public Hospital
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.7759/cureus.22569
dc.subject.decscarcinoma de células escamosas de cabeza y cuello
dc.subject.decs/radioterapia
dc.subject.decsradioterapia guiada por imágenes
dc.relation.publishversionhttp://dx.doi.org/10.7759/cureus.22569
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Fernández-Rodríguez LJ] Department of Medicine, Hospital de Alta Complejidad Virgen de la Puerta, Trujillo, Perú. [Arens-Benites MA] Radiotherapy Center, Hospital de Alta Complejidad Virgen de la Puerta, Trujillo, Perú. [Maldonado-Pijoan X] Servei d’Oncologia Radioteràpica, Vall d'Hebron Hospital Universitari, Barcelona, Spain
dc.identifier.pmid35371637
dc.identifier.wos000768060800015
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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