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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorHidalgo Rivera, Nils jimmy
dc.contributor.authorPando Rau, Elizabeth
dc.contributor.authorAlberti Delgado, Piero Arturo
dc.contributor.authorVidal Fornells, Laura
dc.contributor.authorMata Mata, Rodrigo José
dc.contributor.authorFernandes Montes, Nair Sonia
dc.contributor.authorGomez Jurado, Maria Jose
dc.contributor.authorDopazo Taboada, Cristina
dc.contributor.authorBlanco Cuso, Laia
dc.contributor.authorTasayco Huaman, Stephanie Solange
dc.contributor.authorMolero Richard, Francesc Xavier
dc.contributor.authorBalsells Valls, Joaquin
dc.contributor.authorCharco Torra, Ramon
dc.date.accessioned2022-08-18T06:31:53Z
dc.date.available2022-08-18T06:31:53Z
dc.date.issued2022-07
dc.identifier.citationHidalgo NJ, Pando E, Alberti P, Vidal L, Mata R, Fernandez N, et al. Elevated Serum Triglyceride Levels in Acute Pancreatitis: A Parameter to be Measured and Considered Early. World J Surg. 2022 Jul;46:1758–67.
dc.identifier.issn1432-2323
dc.identifier.urihttp://hdl.handle.net/11351/8011
dc.descriptionAcute pancreatitis; Serum triglyceride
dc.description.abstractBackground The value of serum triglycerides (TGs) related to complications and the severity of acute pancreatitis (AP) has not been clearly defined. Our study aimed to analyze the association of elevated levels of TG with complications and the severity of AP. Methods The demographic and clinical data of patients with AP were prospectively analyzed. TG levels were measured in the first 24 h of admission. Patients were divided into two groups: one with TG values of<200 mg/dL and another with TG≥200 mg/dL. Data on the outcomes of AP were collected. Results From January 2016 to December 2019, 247 cases were included: 200 with TG<200 mg/dL and 47 with TG≥200 mg/dL. Triglyceride levels≥200 mg/dL were associated with respiratory failure (21.3 vs. 10%, p=0.033), renal failure (23.4 vs. 12%, p=0.044), cardiovascular failure (19.1 vs. 7.5%, p=0.025), organ failure (34 vs. 18.5%, p=0.02), persistent organ failure (27.7 vs. 9.5%, p=0.001), multiple organ failure (19.1 vs. 8%, p=0.031), moderately severe and severe AP (68.1 vs. 40.5%, p=0.001), pancreatic necrosis (63.8 vs. 34%, p<0.001), and admission to the intensive care unit (27.7 vs. 9.5%, p=0.003). In the multivariable analysis, a TG level of≥200 mg/dL was independently associated with respiratory, renal, and cardiovascular failure, organ failure, persistent organ failure, multiple organ failure, pancreatic necrosis, severe pancreatitis, and admission to the intensive care unit (p<0.05). Conclusions In our cohort, TG≥200 mg/dL was related to local and systemic complications. Early determinations of TG levels in AP could help identify patients at risk of complications.
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofseriesWorld Journal of Surgery;46
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectPancreatitis - Diagnòstic
dc.subject.meshPancreatitis, Acute Necrotizing
dc.subject.meshTriglycerides
dc.titleElevated Serum Triglyceride Levels in Acute Pancreatitis: A Parameter to be Measured and Considered Early
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1007/s00268-022-06533-w
dc.subject.decspancreatitis aguda necrotizante
dc.subject.decstriglicéridos
dc.relation.publishversionhttps://doi.org/10.1007/s00268-022-06533-w
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Hidalgo NJ, Pando E, Alberti P, Vidal L, Mata R, Fernandez N, Gomez-Jurado MJ, Dopazo C, Blanco L, Balsells J, Charco R] Servei de Cirurgia Hepatobiliopancreàtica i Trasplantaments, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. [Tasayco S, Molero X] Servei d’Aparell Digestiu, Vall d’Hebron Hospital Universitari, Barcelona, Spain
dc.identifier.pmid35355100
dc.identifier.wos000776830600004
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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