Systematic Screening for Tuberculosis Using Molecular Testing on Stool Samples in Acutely Malnourished Children: A Pilot Implementation Study in a High-Burden Drug-Resistant Tuberculosis Country

Nindia, Arlette; Cerezuela, Maria; Sales, Marta; Tchiloka, Ermelinda; SÁNCHEZ-MONTALVÁ, ADRIÁN; Martínez-Campreciós, Joan; Espinosa-Pereiro, Juan; Trigo Esteban, Elena; Sulleiro, Elena; Tórtola Fernández, María Teresa; Oliveira Souto, Inés; Aznar, María Luisa; Molina Romero, Israel

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Systematic Screening for Tuberculosis Using Molecular Testing on Stool Samples in Acutely Malnourished Children: A Pilot Implementation Study in a High-Burden Drug-Resistant Tuberculosis Country, 2025 (407.6Kb)

Date

2025-03

Permanent link

http://hdl.handle.net/11351/12911

DOI

10.1093/ofid/ofaf086

ISSN

2328-8957

WOS

001436355500001

PMID

40046881

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Abstract

Systematic screening of tuberculosis (TB) using molecular testing on stool samples detected TB in 5.2% of acutely malnourished children, including cases without evident clinical symptoms. This screening strategy could enhance TB diagnosis and facilitate prompt treatment initiation in this population. Further studies are required to confirm long-term outcomes and cost-effectiveness.

Keywords

Acute malnutrition; Systematic screening; Tuberculosis

Bibliographic citation

Martínez-Campreciós J, Espinosa-Pereiro J, Nindia A, Cerezuela M, Sales M, Tchiloka E, et al. Systematic Screening for Tuberculosis Using Molecular Testing on Stool Samples in Acutely Malnourished Children: A Pilot Implementation Study in a High-Burden Drug-Resistant Tuberculosis Country. Open Forum Infect Dis. 2025 Mar;12(3):ofaf086.