The need to provide an urgent solution to the problem of bacterial resistance and the lack of effective new treatments has led to the creation of programs to optimize the use of antimicrobials (PROA). One of the objectives of these programs is to promote the duration of effective treatments as short as possible, because the efficacy is maximum in the first days of treatment while the adverse effects (the development of resistance and toxicity) and the expense are they increase as they lengthen. We are witnessing a paradigm shift. There is sufficient evidence to recommend short courses in urinary tract infection, in community-acquired pneumonia and in those associated with mechanical ventilation, in intra-abdominal infection, in acute otitis media and in acute bacterial sinusitis. However, it should be borne in mind that patients with severe immunosuppression, serious infections, infections without surgical control of the focus, infections with multiresistant bacteria, patients without adequate initial response, prosthetic infections, are not candidates for short treatments. infections in locations that are difficult to access for antibiotics. In this Bulletin the recommended durations for the different pathologies are reviewed
Duration; Antibiotics; Resistances
Mòdol-Deltell JM, Álvarez-Martins M, Giménez-Pérez M. Durada del tractament antibiòtic: es pot escurçar amb seguretat. Butll Inf Ter. 2018 Juny;29(06):37-43.
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