In any infectious disease, the administration of a suitable antibiotic treatment in the appropriate and necessary moment is key for the care and evolution of the patient, and also to reduce its morbimortality. Because of that, it is determining that the diagnostic and treatment of the disease were carried out as soon as possible. The increasing incidence of caused infections for resistant pathogens (or multiresistant) to the available antibiotics provokes a high probability of error in its treatment. For instance it happens in the cases of severe infections, the treatment of which, because of being urgent, is usually chosen empirically, without expecting the outcomes of sensitivity. In fact, it is estimated that the choice of the antibiotic, the indications and the duration of the treatment for the infectious diseases are erroneous in 30-50% of the cases. This not only it drives to an increase of the morbimortality of these diseases, but, still more important, it promotes the appearance and dissemination of antimicrobic resistances among the pathogenic microorganisms. Precisely, the high error rate in the treatment of the infectious diseases, together with the uncontrolled use of antibiotics in the last decades has caused that today there is an alarming number of resistant pathogens and, consequently, an increase of the incidence of infectious diseases of difficult treatment and the mortality associated with these ones. Therefore, it is preferential to adopt measures that allow to revert and to control this situation.
MALDI-TOF; Mass spectrometry technology; Diagnosis; Infectious disease
Reig-Viader R, Giménez E. MALDI-TOF en el diagnóstico de las resistencias a antibióticos. Barcelona: Agència de Qualitat i Avaluació Sanitàries de Catalunya; 2019. (Informes, estudios e investigación).
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