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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorMonteagudo, Mònica
dc.contributor.authorBarrecheguren Fernández, Miriam
dc.contributor.authorSolntseva, Iryna
dc.contributor.authorDhalwani, Nafeesa
dc.contributor.authorBooth, Alison
dc.contributor.authorNuñez Dubon, Alexa Gabriela
dc.contributor.authorMiravitlles Fernández, Marc
dc.date.accessioned2021-11-15T09:41:45Z
dc.date.available2021-11-15T09:41:45Z
dc.date.issued2021-03-22
dc.identifier.citationMonteagudo M, Barrecheguren M, Solntseva I, Dhalwani N, Booth A, Nuñez A, et al. Clinical characteristics and factors associated with triple therapy use in newly diagnosed patients with COPD. NPJ Prim Care Respir Med. 2021 Mar 22;31:16.
dc.identifier.issn2055-1010
dc.identifier.urihttp://hdl.handle.net/11351/6540
dc.descriptionChronic obstructive pulmonary disease; Epidemiology
dc.description.abstractThere is limited information about the initiation of triple therapy (TT) in patients with chronic obstructive pulmonary disease (COPD) in primary care. This was an observational, population-based study in patients identified from a primary care electronic medical records database in Catalonia from 2011 to 2015 aimed to identify the use of TT in patients with newly diagnosed COPD. A total of 69,668 newly diagnosed patients were identified of whom 11,524 (16.5%) initiated TT, of whom 8626 initiated TT at or immediately after COPD diagnosis. Among them, 72.3% were GOLD A/B, 14.6% were frequent exacerbators, and 7.1% had asthma–COPD overlap (ACO). Variables associated with TT initiation were: male sex, older age, previous exacerbations, ACO, a previous treatment regimen containing an inhaled corticosteroid, previous pneumonia, and history of lung cancer. A significant number of COPD patients in Primary Care initiated TT shortly after or even before an established COPD diagnosis.
dc.language.isoeng
dc.publisherNature Research
dc.relation.ispartofseriesNPJ Primary Care Respiratory Medicine;31
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectPulmons - Malalties obstructives - Tractament
dc.subjectPulmons - Malalties obstructives - Diagnòstic
dc.subject.meshPulmonary Disease, Chronic Obstructive
dc.subject.mesh/diagnosis
dc.subject.meshDrug Therapy, Combination
dc.titleClinical characteristics and factors associated with triple therapy use in newly diagnosed patients with COPD
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1038/s41533-021-00227-x
dc.subject.decsenfermedad pulmonar obstructiva crónica
dc.subject.decs/diagnóstico
dc.subject.decsfarmacoterapia combinada
dc.relation.publishversionhttps://doi.org/10.1038/s41533-021-00227-x
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Monteagudo M] Primary Care University Research Institute Jordi Gol (IDIAP Jordi Gol), Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Barrecheguren M] Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBER de Enfermedades Respiratorias (CIBERES), Barcelona, Spain. [Solntseva I] Primary Care University Research Institute Jordi Gol (IDIAP Jordi Gol), Barcelona, Spain. [Dhalwani N, Booth A] Evidera, London, UK. [Nuñez A, Miravitlles M] Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBER de Enfermedades Respiratorias (CIBERES), Barcelona, Spain
dc.identifier.pmid33753747
dc.identifier.wos000632053400001
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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