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dc.contributorVall d'Hebron Barcelona Hospital Campus
dc.contributor.authorHermelijn, Sergei
dc.contributor.authorKersten, Casper
dc.contributor.authorMullassery, Dhanya
dc.contributor.authorMuthialu, Nagarajan
dc.contributor.authorCobanoglu, Nazan
dc.contributor.authorGartner Tizzano, Silvia
dc.date.accessioned2021-12-17T11:19:05Z
dc.date.available2021-12-17T11:19:05Z
dc.date.issued2021-04-12
dc.identifier.citationHermelijn S, Kersten C, Mullassery D, Muthialu N, Cobanoglu N, Gartner S, et al. Development of a core outcome set for congenital pulmonary airway malformations: study protocol of an international Delphi survey. BMJ Open. 2021 Apr 12;11:e044544.
dc.identifier.issn2044-6055
dc.identifier.urihttp://hdl.handle.net/11351/6708
dc.descriptionNeonatology; Paediatric surgery; Paediatric thoracic medicine
dc.description.abstractIntroduction A worldwide lack of consensus exists on the optimal management of asymptomatic congenital pulmonary airway malformation (CPAM) even though the incidence is increasing. Either a surgical resection is performed or a wait-and-see policy is employed, depending on the treating physician. Management is largely based on expert opinion and scientific evidence is scarce. Wide variations in outcome measures are seen between studies making comparison difficult thus highlighting the lack of universal consensus in outcome measures as well. We aim to define a core outcome set which will include the most important core outcome parameters for paediatric patients with an asymptomatic CPAM. Methods and analysis This study will include a critical appraisal of the current literature followed by a three-stage Delphi process with two stakeholder groups. One surgical group including paediatric as well as thoracic surgeons, and a non-surgeon group including paediatric pulmonologists, intensive care and neonatal specialists. All participants will score outcome parameters according to their level of importance and the most important parameters will be determined by consensus. Ethics and dissemination Electronic informed consent will be obtained from all participants. Ethical approval is not required. After the core outcome set has been defined, we intend to design an international randomised controlled trial: the COllaborative Neonatal NEtwork for the first CPAM Trial, which will be aimed at determining the optimal management of patients with asymptomatic CPAM.
dc.language.isoeng
dc.publisherBMJ
dc.relation.ispartofseriesBMJ Open;11
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScientia
dc.subjectPulmons - Malalties
dc.subjectProtocols clínics
dc.subjectMalalties congènites
dc.subject.meshDelphi Technique
dc.subject.meshLung Diseases
dc.subject.meshResearch Design
dc.titleDevelopment of a core outcome set for congenital pulmonary airway malformations: study protocol of an international Delphi survey
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1136/bmjopen-2020-044544
dc.subject.decstécnica Delfos
dc.subject.decsenfermedades pulmonares
dc.subject.decsdiseño de la investigación
dc.relation.publishversionhttp://dx.doi.org/10.1136/bmjopen-2020-044544
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.organismesInstitut Català de la Salut
dc.contributor.authoraffiliation[Hermelijn S, Kersten C] Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands. [Mullassery D, Muthialu N] Pediatric Surgery, Great Ormond Street Hospital for Children, London, UK. [Cobanoglu N] Pediatric Pulmonology, Ankara University Faculty of Medicine, Ankara, Turkey. [Gartner S] Servei de Pneumologia Pediàtrica, Vall d'Hebron Hospital Universitari, Barcelona, Spain
dc.identifier.pmid33846152
dc.identifier.wos000641484100005
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


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