dc.contributor | Vall d'Hebron Barcelona Hospital Campus |
dc.contributor.author | Kladnik, Jerneja |
dc.contributor.author | Dolinar, Ana |
dc.contributor.author | Kljun, Jakob |
dc.contributor.author | Perea Pérez, David |
dc.contributor.author | Grau Exposito, Judit |
dc.contributor.author | Genesca Ferrer, Meritxell |
dc.contributor.author | Novinec, Marko |
dc.contributor.author | Buzón Gómez, María José |
dc.contributor.author | Turel, Iztok |
dc.date.accessioned | 2022-12-12T10:50:20Z |
dc.date.available | 2022-12-12T10:50:20Z |
dc.date.issued | 2022-12 |
dc.identifier.citation | Kladnik J, Dolinar A, Kljun J, Perea D, Grau-Expósito J, Genescà M, et al. Zinc pyrithione is a potent inhibitor of PLPro and cathepsin L enzymes with ex vivo inhibition of SARS-CoV-2 entry and replication. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2158–68. |
dc.identifier.issn | 1475-6374 |
dc.identifier.uri | https://hdl.handle.net/11351/8644 |
dc.description | SARS-CoV-2; Inhibició; Zinc |
dc.description.sponsorship | The authors acknowledge the financial support from the Slovenian Research Agency ARRS [Research Core Funding No. P1-0175 together with an increase in research programme funding related to the COVID-19 pandemic], and the grant from the Health Department of the Government of Catalonia [DGRIS 1_5] and the Fundació La Marató TV3 [Grants 202104FMTV3 and 202112FMTV3] to M.G. and MJ.B. MJ.B is supported by the Miguel Servet Program funded by the Spanish Health Institute Carlos III [CP17/00179]. |
dc.language.iso | eng |
dc.publisher | Taylor & Francis |
dc.relation.ispartofseries | Journal of Enzyme Inhibition and Medicinal Chemistry;37(1) |
dc.rights | Attribution 4.0 International |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ |
dc.source | Scientia |
dc.subject | COVID-19 (Malaltia) - Tractament |
dc.subject | Medicaments antivírics - Ús terapèutic |
dc.subject | Compostos organometàl·lics |
dc.subject.mesh | Coronavirus Infections |
dc.subject.mesh | /drug therapy |
dc.subject.mesh | Antiviral Agents |
dc.subject.mesh | Organometallic Compounds |
dc.title | Zinc pyrithione is a potent inhibitor of PLPro and cathepsin L enzymes with ex vivo inhibition of SARS-CoV-2 entry and replication |
dc.type | info:eu-repo/semantics/article |
dc.identifier.doi | 10.1080/14756366.2022.2108417 |
dc.subject.decs | infecciones por Coronavirus |
dc.subject.decs | /farmacoterapia |
dc.subject.decs | antivíricos |
dc.subject.decs | compuestos organometálicos |
dc.relation.publishversion | https://doi.org/10.1080/14756366.2022.2108417 |
dc.type.version | info:eu-repo/semantics/publishedVersion |
dc.audience | Professionals |
dc.contributor.organismes | Institut Català de la Salut |
dc.contributor.authoraffiliation | [Kladnik J, Dolinar A, Kljun J, Novinec M, Turel I] Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia. [Perea D, Grau-Expósito J, Genescà M, Buzon MJ] Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Malalties Infeccioses, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain |
dc.identifier.pmid | 35943189 |
dc.identifier.wos | 000837908400001 |
dc.relation.projectid | info:eu-repo/grantAgreement/ES/PE2013-2016/CP17%2F00179 |
dc.rights.accessrights | info:eu-repo/semantics/openAccess |