Show simple item record

 
dc.contributorConsorci Sanitari de Terrassa
dc.contributor.authorRojas-Lechuga, María Jesús
dc.contributor.authorCeballos Guerra, Juan Carlos
dc.contributor.authorValls Mateus, Meritxell
dc.contributor.authorMackers, Paula
dc.contributor.authorIzquierdo-Domínguez, A
dc.contributor.authorLópez-Chacón, M
dc.date.accessioned2023-06-28T12:24:39Z
dc.date.available2023-06-28T12:24:39Z
dc.date.issued2022-07-22
dc.identifier.citationRojas-Lechuga MJ, Ceballos JC, Valls-Mateus M, Mackers P, Izquierdo-Domínguez A, López-Chacón M, et al. The 8-Odorant Barcelona Olfactory Test (BOT-8): Validation of a New Test in the Spanish Population During the COVID-19 Pandemic. J Investig Allergol Clin Immunol. 2022 Jul 22;32(4):291-8.
dc.identifier.urihttps://hdl.handle.net/11351/9919
dc.descriptionCOVID-19; Loss of smell; Smell test
dc.description.abstractBackground and objective: Most smell tests are difficult to implement in daily clinical practice owing to their long duration. The aim of the present study was to develop and validate a short, easy-to-perform, and reusable smell test to be implemented during the COVID-19 pandemic. Methods: The study population comprised 120 healthy adults and 195 patients with self-reported olfactory dysfunction (OD). The 8-Odorant Barcelona Olfactory Test (BOT-8) was used for detection, memory/recognition, and forced-choice identification. In addition, a rose threshold test was performed, and a visual analog scale was applied. The Smell Diskettes Olfaction Test (SDOT) was used for correlation in healthy volunteers, and the University of Pennsylvania Smell Identification Test (UPSIT) was used for patients with OD to establish cut-offs for anosmia and hyposmia. In order to take account of the COVID-19 pandemic, disposable cotton swabs with odorants were compared with the original test. Results: In healthy persons, the mean (SD) BOT-8 score was 100% for detection, 94.5% (1.07) for memory/recognition, and 89.6% (0.86) for identification. In patients with OD, the equivalent values were 86% (32.8), 73.2% (37.9), and 77.1% (34.2), respectively. BOT-8 demonstrated good test-retest reliability, with agreement of 96.7% and a quadratic k of 0.84 (P<.001). A strong correlation was observed between BOT-8 and SDOT (r=0.67, P<.001) and UPSIT (r=0.86, P<.001). Agreement was excellent for disposable cotton swabs, with a k of 0.79 compared with the original test. The cut-off point for anosmia was ≤3 (area under the curve, 0.83; sensitivity, 0.673; specificity, 0.993). Conclusion: BOT-8 offers an efficient and fast method for assessment of smell threshold, detection, memory, and identification in daily clinical practice. Disposable cotton swabs with odorants proved to be useful and safe during the COVID-19 pandemic.
dc.language.isoeng
dc.publisherEsmon Publicidad
dc.relation.ispartofseriesJournal of Investigational Allergology and Clinical Immunology;32(4)
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceScientia
dc.subjectTrastorns olfactius
dc.subjectCOVID-19 (Malaltia)
dc.subjectOlfactometria
dc.subject.meshOlfaction Disorders
dc.subject.meshOlfactometry
dc.subject.meshCoronavirus Infections
dc.titleThe 8-Odorant Barcelona Olfactory Test (BOT-8): Validation of a New Test in the Spanish Population During the COVID-19 Pandemic
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.18176/jiaci.0824
dc.subject.decstrastornos del olfato
dc.subject.decsolfatometría
dc.subject.decsinfecciones por Coronavirus
dc.relation.publishversionhttps://doi.org/10.18176/jiaci.0824
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.audienceProfessionals
dc.contributor.authoraffiliation[Rojas-Lechuga MJ, López-Chacón M] Rhinology Unit and Smell Clinic, Department of Otorhinolaryngology, Hospital Clinic, Universitat de Barcelona, Spain. Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain. CIBER Respiratory Diseases (CIBERES), Spain. [Ceballos JC] Rhinology Unit and Smell Clinic, Department of Otorhinolaryngology, Hospital Clinic, Universitat de Barcelona, Spain. Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain. [Valls-Mateus M] Department of Otorhinolaryngology, Hospital Universitari Son Espases, Mallorca, Spain. [Mackers P] Department of Otorhinolaryngology, Hospital del Mar, Barcelona, Spain. [Izquierdo-Domínguez A] Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain. Servei d’Alergologia, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain. Unidad Alergo Rino, Centro Médico Teknon, Barcelona, Spain
dc.identifier.pmid35532333
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record