GCN2 inhibition reduces mutant SOD1 clustering and toxicity and delays disease progression in an amyotrophic lateral sclerosis mouse model

Ortiz, Didio Alberto; Peregrín, Nuria; Valencia, Miguel; Vinueza-Gavilanes, Rodrigo; Marin-Ordovas, Elisa; Ferrero, Roberto

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GCN2 inhibition reduces mutant SOD1 clustering and toxicity and delays disease progression in an amyotrophic lateral sclerosis mouse model, 2024 (951.6Kb)

Author

Ortiz, Didio Alberto

Peregrín, Nuria

Valencia, Miguel

Vinueza-Gavilanes, Rodrigo

Marin-Ordovas, Elisa

Ferrero, Roberto

Date

2024-09-20

Permanent link

https://hdl.handle.net/11351/12459

DOI

10.1186/s40035-024-00441-w

ISSN

2047-9158

WOS

001317459900001

PMID

39304897

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Keywords

Toxicity; Mouse model; Amyotrophic lateral sclerosis

Bibliographic citation

Ortiz DA, Peregrín N, Valencia M, Vinueza-Gavilanes R, Marín-Ordovas E, Ferrero R, et al. GCN2 inhibition reduces mutant SOD1 clustering and toxicity and delays disease progression in an amyotrophic lateral sclerosis mouse model. Transl Neurodegener. 2024 Sep 20;13:49.